Engineered exosome for drug delivery: recent development and clinical applications

J Tian, Z Han, D Song, Y Peng, M **ong… - International journal …, 2023 - Taylor & Francis
Exosomes are nano-sized membrane vesicles that transfer bioactive molecules between
cells and modulate various biological processes under physiological and pathological …

Modification of immune cell-derived exosomes for enhanced cancer immunotherapy: current advances and therapeutic applications

I Jung, S Shin, MC Baek, K Yea - Experimental & Molecular Medicine, 2024 - nature.com
Cancer immunotherapy has revolutionized the approach to cancer treatment of malignant
tumors by harnessing the body's immune system to selectively target cancer cells. Despite …

Genetically engineered loaded extracellular vesicles for drug delivery

Z Erana-Perez, M Igartua, E Santos-Vizcaino… - Trends in …, 2024 - cell.com
The use of extracellular vesicles (EVs) for drug delivery is being widely explored by
scientists from several research fields. To fully exploit their therapeutic potential, multiple …

Exosomes: From basic research to clinical diagnostic and therapeutic applications in cancer

S Araujo-Abad, JM Berna, E Lloret-Lopez… - Cellular Oncology, 2024 - Springer
Cancer continues to pose a global threat despite potent anticancer drugs, often
accompanied by undesired side effects. To enhance patient outcomes, sophisticated …

Standardization approaches for extracellular vesicle loading with oligonucleotides and biologics

J Roerig, M Schulz‐Siegmund - Small, 2023 - Wiley Online Library
Extracellular vesicles (EVs) are widely recognized for their potential as drug delivery
systems. EVs are membranous nanoparticles shed from cells. Among their natural features …

Biomimicking extracellular vesicles with fully artificial ones: a rational design of EV-BIOMIMETICS toward effective theranostic tools in nanomedicine

G Rosso, V Cauda - ACS Biomaterials Science & Engineering, 2022 - ACS Publications
Extracellular Vesicles (EVs) are the protagonists in cell communication and membrane
trafficking, being responsible for the delivery of innumerable biomolecules and signaling …

Engineered extracellular vesicles as a targeted delivery platform for precision therapy

Y Sun, F Sun, W Xu, H Qian - Tissue Engineering and Regenerative …, 2023 - Springer
Extracellular vesicles (EVs)-based cell-free strategy has shown therapeutic potential in
tissue regeneration. Due to their important roles in intercellular communications and their …

Physio-chemical modifications to re-engineer small extracellular vesicles for targeted anticancer therapeutics delivery and imaging

R Asfiya, L Xu, A Paramanantham… - ACS Biomaterials …, 2024 - ACS Publications
Cancer theranostics developed through nanoengineering applications are essential for
targeted oncologic interventions in the new era of personalized and precision medicine …

[HTML][HTML] Targeted lipid-coated ZnO nanoparticles coupled with ultrasound: a sonodynamic approach for the treatment of osteosarcoma as 3D spheroid models

M Carofiglio, G Mesiano, G Rosso, M Conte… - Materials Today …, 2024 - Elsevier
Bone cancer is a rare disease with limited treatment options. Surgery and chemotherapy
frequently fail to cure the disease because metastases can develop in the former, and the …

Synergistic phenomena between iron-doped ZnO nanoparticles and shock waves exploited against pancreatic cancer cells

M Carofiglio, M Conte, L Racca… - ACS Applied Nano …, 2022 - ACS Publications
We propose the use of iron-doped zinc oxide nanoparticles (Fe: ZnO NPs) showing
theranostic capabilities and being synergistically active against pancreatic ductal …