OpenSim: Simulating musculoskeletal dynamics and neuromuscular control to study human and animal movement

A Seth, JL Hicks, TK Uchida, A Habib… - PLoS computational …, 2018 - journals.plos.org
Movement is fundamental to human and animal life, emerging through interaction of
complex neural, muscular, and skeletal systems. Study of movement draws from and …

Predictive multibody dynamic simulation of human neuromusculoskeletal systems: a review

M Febrer-Nafría, A Nasr, M Ezati, P Brown… - Multibody System …, 2023 - Springer
Over the past decade, there has been a rapid increase in applications of multibody system
dynamics to the predictive simulation of human movement. Using predictive “what-if” human …

A hip–knee–ankle exoskeleton emulator for studying gait assistance

GM Bryan, PW Franks, SC Klein… - … Journal of Robotics …, 2021 - journals.sagepub.com
Lower-limb exoskeletons could improve the mobility of people with disabilities, older adults,
workers, first responders, and military personnel. Despite recent advances, few products are …

Predicting gait adaptations due to ankle plantarflexor muscle weakness and contracture using physics-based musculoskeletal simulations

CF Ong, T Geijtenbeek, JL Hicks… - PLoS computational …, 2019 - journals.plos.org
Deficits in the ankle plantarflexor muscles, such as weakness and contracture, occur
commonly in conditions such as cerebral palsy, stroke, muscular dystrophy, Charcot-Marie …

Muscle coordination retraining inspired by musculoskeletal simulations reduces knee contact force

SD Uhlrich, RW Jackson, A Seth, JA Kolesar… - Scientific reports, 2022 - nature.com
Humans typically coordinate their muscles to meet movement objectives like minimizing
energy expenditure. In the presence of pathology, new objectives gain importance, like …

Neural data-driven musculoskeletal modeling for personalized neurorehabilitation technologies

M Sartori, DG Llyod, D Farina - IEEE transactions on …, 2016 - ieeexplore.ieee.org
Objectives: The development of neurorehabilitation technologies requires the profound
understanding of the mechanisms underlying an individual's motor ability and impairment. A …

Optimization-based biomechanical lifting models for manual material handling: A comprehensive review

R Zaman, A Arefeen, J Quarnstrom… - Proceedings of the …, 2022 - journals.sagepub.com
Lifting is a main task for manual material handling (MMH), and it is also associated with
lower back pain. There are many studies in the literature on predicting lifting strategies …

Bayesian optimization objective-based experimental design

M Imani, SF Ghoreishi - 2020 American control conference …, 2020 - ieeexplore.ieee.org
Design has become a salient part of most of the scientific and engineering tasks, embracing
a wide range of domains including real experimental settings (eg, material discovery or drug …

A conceptual blueprint for making neuromusculoskeletal models clinically useful

BJ Fregly - Applied Sciences, 2021 - mdpi.com
The ultimate goal of most neuromusculoskeletal modeling research is to improve the
treatment of movement impairments. However, even though neuromusculoskeletal models …

Predictive simulations of neuromuscular coordination and joint-contact loading in human gait

YC Lin, JP Walter, MG Pandy - Annals of biomedical engineering, 2018 - Springer
We implemented direct collocation on a full-body neuromusculoskeletal model to calculate
muscle forces, ground reaction forces and knee contact loading simultaneously for one cycle …