Circulating tumor cell isolation for cancer diagnosis and prognosis

Z Deng, S Wu, Y Wang, D Shi - EBioMedicine, 2022‏ - thelancet.com
Circulating tumor cells (CTCs) are tumor cells that shed from the primary tumor and
intravasate into the peripheral blood circulation system responsible for metastasis. Sensitive …

Aptamer-based detection of circulating targets for precision medicine

L Wu, Y Wang, X Xu, Y Liu, B Lin, M Zhang… - Chemical …, 2021‏ - ACS Publications
The past decade has witnessed ongoing progress in precision medicine to improve human
health. As an emerging diagnostic technique, liquid biopsy can provide real-time …

Analytical device miniaturization for the detection of circulating biomarkers

A Natalia, L Zhang, NR Sundah, Y Zhang… - Nature Reviews …, 2023‏ - nature.com
Diverse (sub) cellular materials are secreted by cells into the systemic circulation at different
stages of disease progression. These circulating biomarkers include whole cells, such as …

Controllable assembly of a quantum dot-based aptasensor guided by CRISPR/Cas12a for direct measurement of circulating tumor cells in human blood

Q Zhang, X Gao, YP Ho, M Liu, Y Han, D Li, H Yuan… - Nano Letters, 2024‏ - ACS Publications
Accurate and sensitive analysis of circulating tumor cells (CTCs) in human blood provides a
non-invasive approach for the evaluation of cancer metastasis and early cancer diagnosis …

Integrated “lab-on-a-chip” microfluidic systems for isolation, enrichment, and analysis of cancer biomarkers

S Surappa, P Multani, U Parlatan, PD Sinawang… - Lab on a Chip, 2023‏ - pubs.rsc.org
The liquid biopsy has garnered considerable attention as a complementary clinical tool for
the early detection, molecular characterization and monitoring of cancer over the past …

Precise Capture and Dynamic Release of Circulating Liver Cancer Cells with Dual‐Histidine‐Based Cell Imprinted Hydrogels

W Sun, X You, X Zhao, X Zhang, C Yang… - Advanced …, 2024‏ - Wiley Online Library
Circulating tumor cells (CTCs) detection presents significant advantages in diagnosing liver
cancer due to its noninvasiveness, real‐time monitoring, and dynamic tracking. However …

Microfluidic systems for particle capture and release: A review

L Gong, A Cretella, Y Lin - Biosensors and Bioelectronics, 2023‏ - Elsevier
Microfluidic technology has emerged as a promising tool in various applications, including
biosensing, disease diagnosis, and environmental monitoring. One of the notable features of …

Harnessing virus flexibility to selectively capture and profile rare circulating target cells for precise cancer subty**

HD Li, YQ Chen, Y Li, X Wei, SY Wang, Y Cao… - Nature …, 2024‏ - nature.com
The effective isolation of rare target cells, such as circulating tumor cells, from whole blood is
still challenging due to the lack of a capturing surface with strong target-binding affinity and …

Multifunctional branched nanostraw-electroporation platform for intracellular regulation and monitoring of circulating tumor cells

G He, J Feng, A Zhang, L Zhou, R Wen, J Wu… - Nano …, 2019‏ - ACS Publications
Downstream analysis of circulating tumor cells (CTCs) has provided new insights into
cancer research. In particular, the detection of CTCs, followed by the regulation and …

Recapitulating dynamic ECM ligand presentation at biomaterial interfaces: Molecular strategies and biomedical prospects

W He, Q Wang, X Tian, G Pan - Exploration, 2022‏ - Wiley Online Library
The extracellular matrix (ECM) provides not only physical support for the tissue structural
integrity, but also dynamic biochemical cues capable of regulating diverse cell behaviors …