DNA functional materials assembled from branched DNA: design, synthesis, and applications

Y Dong, C Yao, Y Zhu, L Yang, D Luo… - Chemical Reviews, 2020 - ACS Publications
DNA is traditionally known as a central genetic biomolecule in living systems. From an
alternative perspective, DNA is a versatile molecular building-block for the construction of …

DNA nanotechnology-enabled drug delivery systems

Q Hu, H Li, L Wang, H Gu, C Fan - Chemical reviews, 2018 - ACS Publications
Over the past decade, we have seen rapid advances in applying nanotechnology in
biomedical areas including bioimaging, biodetection, and drug delivery. As an emerging …

DNA origami: scaffolds for creating higher order structures

F Hong, F Zhang, Y Liu, H Yan - Chemical reviews, 2017 - ACS Publications
DNA has become one of the most extensively used molecular building blocks for
engineering self-assembling materials. DNA origami is a technique that uses hundreds of …

The biological applications of DNA nanomaterials: current challenges and future directions

W Ma, Y Zhan, Y Zhang, C Mao, X **e… - Signal transduction and …, 2021 - nature.com
DNA, a genetic material, has been employed in different scientific directions for various
biological applications as driven by DNA nanotechnology in the past decades, including …

Programmable materials and the nature of the DNA bond

MR Jones, NC Seeman, CA Mirkin - Spherical Nucleic Acids, 2020 - api.taylorfrancis.com
A grand challenge in the fields of chemistry and materials science is the ability to construct f
the plac or a giv ement of en application. each component in or materials with absolute …

Control of DNA strand displacement kinetics using toehold exchange

DY Zhang, E Winfree - Journal of the American Chemical Society, 2009 - ACS Publications
DNA is increasingly being used as the engineering material of choice for the construction of
nanoscale circuits, structures, and motors. Many of these enzyme-free constructions function …

Synthesis from DNA of a molecule with the connectivity of a cube

J Chen, NC Seeman - Nature, 1991 - nature.com
A PRINCIPAL goal of biotechnology is the assembly of novel biomaterials for analytical,
industrial and therapeutic purposes. The advent of stable immobile nucleic acid branched …

DNA nanotechnology

NC Seeman, HF Sleiman - Nature Reviews Materials, 2017 - nature.com
DNA is the molecule that stores and transmits genetic information in biological systems. The
field of DNA nanotechnology takes this molecule out of its biological context and uses its …

Challenges and opportunities for structural DNA nanotechnology

AV Pinheiro, D Han, WM Shih, H Yan - Nature nanotechnology, 2011 - nature.com
DNA molecules have been used to build a variety of nanoscale structures and devices over
the past 30 years, and potential applications have begun to emerge. But the development of …

Designer nanoscale DNA assemblies programmed from the top down

R Veneziano, S Ratanalert, K Zhang, F Zhang, H Yan… - Science, 2016 - science.org
INTRODUCTION Synthetic DNA can be programmed by using canonical Watson-Crick base
pairing to form highly structured nanometer-scale assemblies that rival many natural protein …