CD44, a cell-surface glycoprotein, has long been studied as a cancer molecule due to its
essential role in physiological activities in normal cells and pathological activities in cancer …

Cell-adhesion molecules, once believed to function primarily in tethering cells to
extracellular ligands, are now recognized as having broader functions in cellular signalling …

Cancer stem cell population is a subset of cells capable of dictating invasion, metastasis,
heterogeneity, and therapeutic resistance in tumours. Eradication of this rare population is a …

Prostate cancer has the highest prevalence of any nonskin cancer in the human body, with
similar likelihood of neoplastic foci found within the prostates of men around the world …

Metastasis, the spread of malignant cells from a primary tumor to distant sites, poses the
biggest problem to cancer treatment and is the main cause of death of cancer patients. It …

CD44 is a multifunctional protein involved in cell adhesion and signaling. The role of CD44
in prostate cancer (PCa) development and progression is controversial with studies showing …

CD44 is a multistructural and multifunctional cell surface molecule involved in cell
proliferation, cell differentiation, cell migration, angiogenesis, presentation of cytokines …

Members of the CD44 family of transmembrane glycoproteins, in particular CD44v6
isoforms, were shown to be metastatic determinants of rat pancreatic tumour cells back in …

This review focuses on new findings and controversial issues in the pathology and
molecular biology of adenocarcinoma of the prostate. Since management of high-grade …

CD44 has been the subject of extensive research for more than 3 decades because of its
role in breast cancer, in addition to many physiological processes, but interestingly …