Mass spectrometry for neurosurgery: Intraoperative support in decision‐making
SI Pekov, DS Bormotov, SI Bocharova… - Mass Spectrometry …, 2025 - Wiley Online Library
Ambient ionization mass spectrometry was proved to be a powerful tool for oncological
surgery. Still, it remains a translational technique on the way from laboratory to clinic. Brain …
surgery. Still, it remains a translational technique on the way from laboratory to clinic. Brain …
Insight into new opportunities in intra-surgical diagnostics of brain tumors
Brain tumor removal is a crucial step in therapeutic regimens. In surgical interventions, the
ultimate goal is to completely resect the malignant lesion with a safe margin of healthy …
ultimate goal is to completely resect the malignant lesion with a safe margin of healthy …
Incorporation of a disposable ESI emitter into inline cartridge extraction mass spectrometry improves throughput and spectra stability
DS Bormotov, VA Eliferov, OV Peregudova… - Journal of the …, 2022 - ACS Publications
Rapid and reliable methods for detecting tumor margins are crucial for neuro-oncology.
Several mass spectrometry-based methods have been recently proposed to address this …
Several mass spectrometry-based methods have been recently proposed to address this …
Rapid estimation of tumor cell percentage in brain tissue biopsy samples using inline cartridge extraction mass spectrometry
Tumor cell percentage (TCP) is an essential characteristic of biopsy samples that directly
affects the sensitivity of molecular testing in clinical practice. Apart from clarifying diagnoses …
affects the sensitivity of molecular testing in clinical practice. Apart from clarifying diagnoses …
Assessment of variation of inline cartridge extraction mass spectra
ES Zhvansky, VA Eliferov, AA Sorokin… - Journal of Mass …, 2021 - Wiley Online Library
Recently, mass‐spectrometry methods show its utility in tumor boundary location. The effect
of differences between research and clinical protocols such as low‐and high‐resolution …
of differences between research and clinical protocols such as low‐and high‐resolution …
Analysis of phosphatidylcholines alterations in human glioblastomas ex vivo
The analysis of data obtained using ambient mass spectrometric profiling of clinical samples
of primary and secondary human glioblastomas ex vivo, revealed changes in the lipid …
of primary and secondary human glioblastomas ex vivo, revealed changes in the lipid …
Aggregation of Multimodal ICE-MS Data into Joint Classifier Increases Quality of Brain Cancer Tissue Classification
Mass spectrometry fingerprinting combined with multidimensional data analysis has been
proposed in surgery to determine if a biopsy sample is a tumor. In the specific case of brain …
proposed in surgery to determine if a biopsy sample is a tumor. In the specific case of brain …
Lipid Profiles of Human Brain Tumors Obtained by High-Resolution Negative Mode Ambient Mass Spectrometry
Alterations in cell metabolism, including changes in lipid composition occurring during
malignancy, are well characterized for various tumor types. However, a significant part of …
malignancy, are well characterized for various tumor types. However, a significant part of …
The lightweight spherical samplers for simplified collection, storage, and ambient ionization of drugs from saliva and blood
The continuous monitoring of health conditions before, during, and after spaceflight is an
important task in gravitational physiology. Thus a simple, non-invasive method for biological …
important task in gravitational physiology. Thus a simple, non-invasive method for biological …
Comparison of Dimensionality Reduction Methods in Mass Spectra of Astrocytoma and Glioblastoma Tissues
Recently developed methods of ambient ionization allow the collection of mass
spectrometric datasets for biological and medical applications at an unprecedented pace …
spectrometric datasets for biological and medical applications at an unprecedented pace …