Turnitin
降AI改写
早检测系统
早降重系统
Turnitin-UK版
万方检测-期刊版
维普编辑部版
Grammarly检测
Paperpass检测
checkpass检测
PaperYY检测
Inhibition of mitochondrial beta-oxidation as a mechanism of hepatotoxicity
B Fromenty, D Pessayre - Pharmacology & therapeutics, 1995 - Elsevier
Severe and prolonged impairment of mitochondrial β-oxidation leads to microvesicular
steatosis, and, in severe forms, to liver failure, coma and death. Impairment of mitochondrial …
steatosis, and, in severe forms, to liver failure, coma and death. Impairment of mitochondrial …
Impaired mitochondrial function in microvesicular steatosis effects of drugs, ethanol, hormones and cytokines
B Fromenty, D Pessayre - Journal of hepatology, 1997 - Elsevier
Microvesicular steatosis occurs in conditions characterized by severe impairment of the
mitochondrial β-oxidation process, due to genetic and/or acquired causes. Drugs and some …
mitochondrial β-oxidation process, due to genetic and/or acquired causes. Drugs and some …
Acute and chronic hepatic steatosis lead to in vivo lipid peroxidation in mice
P Lettéron, B Fromenty, T Benoît, C Degott… - Journal of …, 1996 - Elsevier
Background/Aims: Several liver diseases that are characterized by chronic steatosis lead to
steatohepatitis lesions in some susceptible subjects. We tested the hypothesis that acute or …
steatohepatitis lesions in some susceptible subjects. We tested the hypothesis that acute or …
Drug-induced liver injury in obesity and nonalcoholic fatty liver disease
Obesity is commonly associated with nonalcoholic fatty liver (NAFL), a benign condition
characterized by hepatic lipid accumulation. However, NAFL can progress in some patients …
characterized by hepatic lipid accumulation. However, NAFL can progress in some patients …
[PDF][PDF] Inhibition of microsomal triglyceride transfer protein: another mechanism for drug‐induced steatosis in mice
Although many steatogenic drugs inhibit mitochondrial fatty acid β‐oxidation, limited
information is available on possible effects on hepatic lipoprotein secretion. In the …
information is available on possible effects on hepatic lipoprotein secretion. In the …
Animal models of nonalcoholic fatty liver disease and steatohepatitis
AA Nanji - Clinics in liver disease, 2004 - liver.theclinics.com
Nonalcoholic fatty liver disease (NAFLD) is an increasingly recognized condition that may
progress to end-stage liver disease. It is characterized by its association with obesity …
progress to end-stage liver disease. It is characterized by its association with obesity …
[PDF][PDF] New insights into the mechanism of bile acid—induced biliary lipid secretion
The hepatocyte is a polarized cell with a distinct basolateral and an apical (bile canalicular)
domain. Transport processes at the two poles of the cell show a high degree of specifi~ ity.' …
domain. Transport processes at the two poles of the cell show a high degree of specifi~ ity.' …
Lipid flow in bile formation
R Coleman, K Rahman - Biochimica et Biophysica Acta (BBA)-Lipids and …, 1992 - Elsevier
One of the most important activities of the liver is the secretion of bile. Bile is both a secretory
and an excretory fluid. Probably its two most important functions being the delivery to the …
and an excretory fluid. Probably its two most important functions being the delivery to the …
Effects of the anticonvulsant drug valproic acid and related substances on the early development of the zebrafish (Brachydanio rerio)
K Herrmann - Toxicology in vitro, 1993 - Elsevier
The early development of the zebrafish Brachydanio rerio is being investigated as a
possible test system for prescreening drugs suspected to be hazardous to humans …
possible test system for prescreening drugs suspected to be hazardous to humans …
Mice without phosphatidylcholine transfer protein have no defects in the secretion of phosphatidylcholine into bile or into lung airspaces
Phosphatidylcholine transfer protein (Pc-tp) is a highly specific carrier of
phosphatidylcholine (PC) without known function. Proposed functions include the supply of …
phosphatidylcholine (PC) without known function. Proposed functions include the supply of …