Supramolecular helical systems: helical assemblies of small molecules, foldamers, and polymers with chiral amplification and their functions
E Yashima, N Ousaka, D Taura, K Shimomura… - Chemical …, 2016 - ACS Publications
In this review, we describe the recent advances in supramolecular helical assemblies
formed from chiral and achiral small molecules, oligomers (foldamers), and helical and …
formed from chiral and achiral small molecules, oligomers (foldamers), and helical and …
Aromatic amide foldamers: structures, properties, and functions
DW Zhang, X Zhao, JL Hou, ZT Li - Chemical reviews, 2012 - ACS Publications
The past several decades have witnessed great progress in the understanding of the high-
order structure of biomacromolecules. Currently, it is well-recognized that folding of proteins …
order structure of biomacromolecules. Currently, it is well-recognized that folding of proteins …
Synthetic foldamers
G Guichard, I Huc - Chemical Communications, 2011 - pubs.rsc.org
Foldamers are artificial folded molecular architectures inspired by the structures and
functions of biopolymers. This highlight focuses on important developments concerning …
functions of biopolymers. This highlight focuses on important developments concerning …
A field guide to foldamers
The breadth of structure and function displayed by the molecules of biology is remarkable.
Considering that there are only three major biopolymer backbones (proteins, ribonucleic …
Considering that there are only three major biopolymer backbones (proteins, ribonucleic …
β-Peptides: from structure to function
In recent years, our understanding of protein structure and function has advanced rapidly,
providing a mechanistic understanding of a wide variety of biological processes. As an …
providing a mechanistic understanding of a wide variety of biological processes. As an …
Synthetic helical polymers: conformation and function
T Nakano, Y Okamoto - Chemical Reviews, 2001 - ACS Publications
The high functionalities of naturally occurring macromolecules such as proteins and genes
arise from their precisely ordered stereostructures. 1 In such systems, the helix is often found …
arise from their precisely ordered stereostructures. 1 In such systems, the helix is often found …
Iterative design of a helically folded aromatic oligoamide sequence for the selective encapsulation of fructose
N Chandramouli, Y Ferrand, G Lautrette… - Nature Chemistry, 2015 - nature.com
The ab initio design of synthetic molecular receptors for a specific biomolecular guest
remains an elusive objective, particularly for targets such as monosaccharides, which have …
remains an elusive objective, particularly for targets such as monosaccharides, which have …
Aromatic oligoamide foldamers
I Huc - European Journal of Organic Chemistry, 2004 - Wiley Online Library
Aromatic oligoamide foldamers possess a high potential for mimicking the secondary
structures of biopolymers. These oligomers are efficiently designed, easy to synthesize, and …
structures of biopolymers. These oligomers are efficiently designed, easy to synthesize, and …
Therapeutic potential of foldamers: from chemical biology tools to drug candidates?
Over the past decade, foldamers have progressively emerged as useful architectures to
mimic secondary structures of proteins. Peptidic foldamers, consisting of various amino acid …
mimic secondary structures of proteins. Peptidic foldamers, consisting of various amino acid …
Aromatic δ-peptides
Oligoamides of 8-amino-2-carboxy-quinoline adopt a very stable helical conformation
characterized in solution by 1H NMR and in the solid state by single-crystal X-ray diffraction …
characterized in solution by 1H NMR and in the solid state by single-crystal X-ray diffraction …