Gut microbiome–brain alliance: a landscape view into mental and gastrointestinal health and disorders

JM Sasso, RM Ammar, R Tenchov… - ACS Chemical …, 2023 - ACS Publications
Gut microbiota includes a vast collection of microorganisms residing within the
gastrointestinal tract. It is broadly recognized that the gut and brain are in constant …

Circadian rhythms and disorders of the timing of sleep

N Meyer, AG Harvey, SW Lockley, DJ Dijk - The Lancet, 2022 - thelancet.com
The daily alternation between sleep and wakefulness is one of the most dominant features
of our lives and is a manifestation of the intrinsic 24 h rhythmicity underlying almost every …

Astrocyte energy and neurotransmitter metabolism in Alzheimer's disease: integration of the glutamate/GABA-glutamine cycle

JV Andersen, A Schousboe, A Verkhratsky - Progress in neurobiology, 2022 - Elsevier
Astrocytes contribute to the complex cellular pathology of Alzheimer's disease (AD).
Neurons and astrocytes function in close collaboration through neurotransmitter recycling …

Time-restricted eating for the prevention and management of metabolic diseases

ENC Manoogian, LS Chow, PR Taub… - Endocrine …, 2022 - academic.oup.com
Time-restricted feeding (TRF, animal-based studies) and time-restricted eating (TRE,
humans) are an emerging behavioral intervention approach based on the understanding of …

Functions of gut microbiota metabolites, current status and future perspectives

J Liu, Y Tan, H Cheng, D Zhang, W Feng… - Aging and …, 2022 - pmc.ncbi.nlm.nih.gov
Gut microbiota, a collection of microorganisms that live within gastrointestinal tract, provides
crucial signaling metabolites for the physiological of hosts. In healthy state, gut microbiota …

Circadian rhythm as a therapeutic target

W Ruan, X Yuan, HK Eltzschig - Nature Reviews Drug Discovery, 2021 - nature.com
The circadian clock evolved in diverse organisms to integrate external environmental
changes and internal physiology. The clock endows the host with temporal precision and …

Circadian rhythms in neurodegenerative disorders

M Nassan, A Videnovic - Nature Reviews Neurology, 2022 - nature.com
Endogenous biological clocks, orchestrated by the suprachiasmatic nucleus, time the
circadian rhythms that synchronize physiological and behavioural functions in humans. The …

Circadian mechanisms in medicine

R Allada, J Bass - New England Journal of Medicine, 2021 - Mass Medical Soc
Circadian Mechanisms in Medicine Molecular insights into diurnal variations in human
physiology and behavior are extending our understanding of a wide range of disease …

Magnesium and the brain: A focus on neuroinflammation and neurodegeneration

JAM Maier, L Locatelli, G Fedele, A Cazzaniga… - International journal of …, 2022 - mdpi.com
Magnesium (Mg) is involved in the regulation of metabolism and in the maintenance of the
homeostasis of all the tissues, including the brain, where it harmonizes nerve signal …

Circadian rhythm sleep–wake disturbances and depression in young people: implications for prevention and early intervention

JJ Crouse, JS Carpenter, YJC Song, SJ Hockey… - The Lancet …, 2021 - thelancet.com
A rate-limiting step in the prevention and early intervention of depressive disorders in young
people is our insufficient understanding of causal mechanisms. One plausible …