Progression through the RNA polymerase II CTD cycle
S Buratowski - Molecular cell, 2009 - cell.com
The C-terminal domain of RNA polymerase II's largest subunit undergoes dynamic
phosphorylation during transcription, and the different phosphorylation patterns that …
phosphorylation during transcription, and the different phosphorylation patterns that …
The RNA polymerase II CTD coordinates transcription and RNA processing
The C-terminal domain (CTD) of the RNA polymerase II largest subunit consists of multiple
heptad repeats (consensus Tyr1–Ser2–Pro3–Thr4–Ser5–Pro6–Ser7), varying in number …
heptad repeats (consensus Tyr1–Ser2–Pro3–Thr4–Ser5–Pro6–Ser7), varying in number …
Identification of Integrator-PP2A complex (INTAC), an RNA polymerase II phosphatase
INTRODUCTION RNA cleavage and phosphorylation-dephosphorylation of the RNA
polymerase II (Pol II) C-terminal domain (CTD) are two regulatory mechanisms of …
polymerase II (Pol II) C-terminal domain (CTD) are two regulatory mechanisms of …
Histone sumoylation and chromatin dynamics
HY Ryu, M Hochstrasser - Nucleic Acids Research, 2021 - academic.oup.com
Chromatin structure and gene expression are dynamically controlled by post-translational
modifications (PTMs) on histone proteins, including ubiquitylation, methylation, acetylation …
modifications (PTMs) on histone proteins, including ubiquitylation, methylation, acetylation …
The RNA polymerase II carboxy-terminal domain (CTD) code
D Eick, M Geyer - Chemical reviews, 2013 - ACS Publications
The smallest viable unit of life is the cell. From bacteria to mammals, all cells use the same
nucleic acid-based universal code for the maintenance and inheritance of genetic …
nucleic acid-based universal code for the maintenance and inheritance of genetic …
Genomics and evolution of protein phosphatases
Protein phosphatases are the essential opposite to protein kinases; together, these enzymes
regulate all protein phosphorylation and most cellular processes. To better understand the …
regulate all protein phosphorylation and most cellular processes. To better understand the …
TFIIH: when transcription met DNA repair
E Compe, JM Egly - Nature reviews Molecular cell biology, 2012 - nature.com
The transcription initiation factor TFIIH is a remarkable protein complex that has a
fundamental role in the transcription of protein-coding genes as well as during the DNA …
fundamental role in the transcription of protein-coding genes as well as during the DNA …
The pol II CTD: new twists in the tail
J Zaborowska, S Egloff, S Murphy - Nature structural & molecular …, 2016 - nature.com
The C-terminal domain (CTD) of the large subunit of RNA polymerase (pol) II comprises
conserved heptad repeats, and post-translational modification of the CTD regulates …
conserved heptad repeats, and post-translational modification of the CTD regulates …
Set2 methylation of histone H3 lysine 36 suppresses histone exchange on transcribed genes
Set2-mediated methylation of histone H3 at Lys 36 (H3K36me) is a co-transcriptional event
that is necessary for the activation of the Rpd3S histone deacetylase complex, thereby …
that is necessary for the activation of the Rpd3S histone deacetylase complex, thereby …
Dynamic phosphorylation patterns of RNA polymerase II CTD during transcription
M Heidemann, C Hintermair, K Voß, D Eick - Biochimica et Biophysica Acta …, 2013 - Elsevier
The eukaryotic RNA polymerase II (RNAPII) catalyzes the transcription of all protein
encoding genes and is also responsible for the generation of small regulatory RNAs. RNAPII …
encoding genes and is also responsible for the generation of small regulatory RNAs. RNAPII …