Viscosity-dependent control of protein synthesis and degradation

Y Chen, JH Huang, C Phong, JE Ferrell Jr - Nature Communications, 2024 - nature.com
It has been proposed that the concentration of proteins in the cytoplasm maximizes the
speed of important biochemical reactions. Here we have used Xenopus egg extracts, which …

Robust trigger wave speed in Xenopus cytoplasmic extracts

JH Huang, Y Chen, WYC Huang, S Tabatabaee… - Nature …, 2024 - nature.com
Self-regenerating trigger waves can spread rapidly through the crowded cytoplasm without
diminishing in amplitude or speed, providing consistent, reliable, long-range …

In vitro cell cycle oscillations exhibit a robust and hysteretic response to changes in cytoplasmic density

M **, F Tavella, S Wang, Q Yang - … of the National Academy of Sciences, 2022 - pnas.org
Cells control the properties of the cytoplasm to ensure proper functioning of biochemical
processes. Recent studies showed that cytoplasmic density varies in both physiological and …