Exploring Potential Epigenetic Biomarkers for Colorectal Cancer Metastasis

P Ajithkumar, SS Vasantharajan, S Pattison… - International journal of …, 2024 - mdpi.com
Metastatic progression is a complex, multistep process and the leading cause of cancer
mortality. There is growing evidence that emphasises the significance of epigenetic …

The Use of Schisandrin B to Combat Triple-Negative Breast Cancers by Inhibiting NLRP3-Induced Interleukin-1β Production

CM Chang, TR Liang, HYP Lam - Biomolecules, 2024 - mdpi.com
Triple-negative breast cancer (TNBC) is the most aggressive and fatal breast cancer
subtype. Nowadays, chemotherapy remains the standard treatment of TNBC, and …

HPV-Negative and HPV-Positive Oral Cancer Cells Stimulate the Polarization of Neutrophils towards Different Functional Phenotypes In Vitro

MG Martínez-Barajas, LF Jave-Suárez… - Cancers, 2023 - mdpi.com
Simple Summary Tumor-associated neutrophils (TANs) participate in the initiation and
development of cancer by exerting either anti-tumorigenic or pro-tumorigenic roles …

Epigenetics of epithelial to mesenchymal transition (EMT) in cancer

KSK Satheesh, H Rani, MK Jolly… - Epigenetics and …, 2021 - Elsevier
Abstract Epithelial to Mesenchymal Transition (EMT) is an evolutionarily conserved
developmental program that confers metastatic properties to cancer cells through the …

Image quantification technique reveals novel lung cancer cytoskeletal phenotype with partial EMT signature

A Basu, MK Paul, M Alioscha-Perez, A Grosberg… - bioRxiv, 2021 - biorxiv.org
Epithelial-mesenchymal Transition (EMT) is a multi-step process that involves cytoskeletal
rearrangement. Here, using novel image quantification tools, we have identified an …

The role of IL-1 in tumor growth and angiogenesis

K Bhadresha, PK Shukla, P Singh - Multifaceted Role of IL-1 in Cancer and …, 2023 - Elsevier
Inflammation is a vital element of the tumor microenvironment. The interleukin-1 (IL-1) family
cytokines are the crucial orchestrators of inflammation and play a key role in tumor initiation …