The cell-free layer in microvascular blood flow

S Kim, PK Ong, O Yalcin, M Intaglietta… - …, 2009 - content.iospress.com
This review discusses the cell-free layer at the wall of the microcirculatory vessels with
emphasis on the influence of blood rheological parameters on its formation as well as its …

Deformation of red blood cells, air bubbles, and droplets in microfluidic devices: Flow visualizations and measurements

D Bento, RO Rodrigues, V Faustino, D Pinho… - Micromachines, 2018 - mdpi.com
Techniques, such as micropipette aspiration and optical tweezers, are widely used to
measure cell mechanical properties, but are generally labor-intensive and time-consuming …

Effects of erythrocyte deformability and aggregation on the cell free layer and apparent viscosity of microscopic blood flows

J Zhang, PC Johnson, AS Popel - Microvascular research, 2009 - Elsevier
Concentrated erythrocyte (ie, red blood cell) suspensions flowing in microchannels have
been simulated with an immersed-boundary lattice Boltzmann algorithm, to examine the cell …

Temporal and spatial variations of cell-free layer width in arterioles

S Kim, RL Kong, AS Popel… - American Journal of …, 2007 - journals.physiology.org
Separation of red blood cells and plasma in microcirculatory vessels produces a cell-free
layer at the wall. This layer may be an important determinant of blood viscosity and wall …

Blood–plasma separation in Y-shaped bifurcating microfluidic channels: a dissipative particle dynamics simulation study

X Li, AS Popel, GE Karniadakis - Physical biology, 2012 - iopscience.iop.org
The motion of a suspension of red blood cells (RBCs) flowing in a Y-shaped bifurcating
microfluidic channel is investigated using a validated low-dimensional RBC model based on …

Role of red blood cell flow behavior in hemodynamics and hemostasis

G Barshtein, R Ben-Ami, S Yedgar - Expert Review of …, 2007 - Taylor & Francis
The primary role of red blood cells (RBCs) is to transport oxygen to the tissues, which is
performed predominantly in the blood capillaries. However, RBCs have unique flow …

Flow visualization: state-of-the-art development of micro-particle image velocimetry

A Etminan, YS Muzychka, K Pope… - Measurement …, 2022 - iopscience.iop.org
Experimental flow visualization is a valuable tool for analyzing microfluidics and nanofluidics
in a wide variety of applications. Since the late 1990s, considerable advances in optical …

The effect of red blood cell aggregation on velocity and cell-depleted layer characteristics of blood in a bifurcating microchannel

JM Sherwood, J Dusting, E Kaliviotis, S Balabani - Biomicrofluidics, 2012 - pubs.aip.org
Red blood cell (RBC) aggregation is a multifaceted phenomenon, and whether it is
generally beneficial or deleterious remains unclear. In order to better understand its effect on …

In vitro particulate analogue fluids for experimental studies of rheological and hemorheological behavior of glucose-rich RBC suspensions

D Pinho, L Campo-Deano, R Lima, FT Pinho - Biomicrofluidics, 2017 - pubs.aip.org
Suspensions of healthy and pathological red blood cells (RBC) flowing in microfluidic
devices are frequently used to perform in vitro blood experiments for a better understanding …

Effect of erythrocyte aggregation and flow rate on cell-free layer formation in arterioles

PK Ong, B Namgung, PC Johnson… - American Journal of …, 2010 - journals.physiology.org
Formation of a cell-free layer is an important dynamic feature of microcirculatory blood flow,
which can be influenced by rheological parameters, such as red blood cell aggregation and …