Post‐transcriptional regulation of messenger RNAs (mRNAs)(ie, mechanisms that control
translation, stability and localization) is a critical focal point in spatiotemporal regulation of …

3′ RNA decay pathways are critical for quality control and regulation of gene expression.
Structural and biochemical studies have provided insights into the key nucleases that carry …

Motivation Identifying the functional sites of a protein, such as the binding sites of proteins,
peptides, or other biological components, is crucial for understanding related biological …

The accurate prediction of protein structures achieved by deep learning (DL) methods is a
significant milestone and has deeply impacted structural biology. Shortly after its release …

Removal of the 5′ end cap is a critical determinant controlling mRNA stability and efficient
gene expression. Removal of the cap is exquisitely controlled by multiple direct and indirect …

The 5′-terminal cap is a fundamental determinant of eukaryotic gene expression which
facilitates cap-dependent translation and protects mRNAs from exonucleolytic degradation …

Although eukaryotic messenger RNAs (mRNAs) normally possess a 5′ end N 7-methyl
guanosine (m 7 G) cap, a non-canonical 5′ nicotinamide adenine dinucleotide (NAD+) cap …

Crosslinking mass spectrometry (XL-MS) is becoming an increasingly popular technique for
modeling protein monomers and complexes. The distance restraints garnered from these …

Decap** is the enzymatic removal of 5′ cap structures from mRNAs in eukaryotic cells.
Cap structures normally enhance mRNA translation and stability, and their excision commits …

A single Dcp1–Dcp2 decap** enzyme targets diverse classes of yeast mRNAs for
decap**-dependent 5′ to 3′ decay, but the molecular mechanisms controlling mRNA …