Infectious keratitis: an update on epidemiology, causative microorganisms, risk factors, and antimicrobial resistance

DSJ Ting, CS Ho, R Deshmukh, DG Said, HS Dua - Eye, 2021 - nature.com
Corneal opacity is the 5th leading cause of blindness and visual impairment globally,
affecting~ 6 million of the world population. In addition, it is responsible for 1.5–2.0 million …

Tfos dews ii pathophysiology report

AJ Bron, CS de Paiva, SK Chauhan, S Bonini… - The ocular …, 2017 - Elsevier
Abstract The TFOS DEWS II Pathophysiology Subcommittee reviewed the mechanisms
involved in the initiation and perpetuation of dry eye disease. Its central mechanism is …

The pathophysiology of dry eye disease: what we know and future directions for research

SC Pflugfelder, CS de Paiva - Ophthalmology, 2017 - Elsevier
Clinical and laboratory studies performed over the past few decades have discovered that
dry eye is a chronic inflammatory disease that can be initiated by numerous extrinsic or …

Coagulase-negative staphylococci

K Becker, C Heilmann, G Peters - Clinical microbiology reviews, 2014 - Am Soc Microbiol
The definition of the heterogeneous group of coagulase-negative staphylococci (CoNS) is
still based on diagnostic procedures that fulfill the clinical need to differentiate between …

Contact lens technology: from fundamentals to applications

R Moreddu, D Vigolo, AK Yetisen - Advanced healthcare …, 2019 - Wiley Online Library
Contact lenses are ocular prosthetic devices used by over 150 million people worldwide.
Primary applications of contact lenses include vision correction, therapeutics, and cosmetics …

An ocular commensal protects against corneal infection by driving an interleukin-17 response from mucosal γδ T cells

AJS Leger, JV Desai, RA Drummond, A Kugadas… - Immunity, 2017 - cell.com
Mucosal sites such as the intestine, oral cavity, nasopharynx, and vagina all have
associated commensal flora. The surface of the eye is also a mucosal site, but proof of a …

The ocular microbiome and microbiota and their effects on ocular surface pathophysiology and disorders

P Aragona, C Baudouin, JMB Del Castillo… - Survey of …, 2021 - Elsevier
The ocular surface flora perform an important role in the defense mechanisms of the ocular
surface system. Its regulation of the immunological activity and the barrier effect against …

Prospective trial of intense pulsed light for the treatment of meibomian gland dysfunction

JP Craig, YH Chen… - … ophthalmology & visual …, 2015 - iovs.arvojournals.org
Purpose.: To evaluate the effect of intense pulsed light (IPL) applied to the periocular area
for meibomian gland dysfunction (MGD) in a prospective, double-masked, placebo …

Current evidence on the ocular surface microbiota and related diseases

F Petrillo, D Pignataro, MA Lavano, B Santella… - Microorganisms, 2020 - mdpi.com
The ocular surface microbiota refers to the resident non-pathogenic microorganisms that
colonize conjunctiva and cornea. Several studies have shown that ocular surface epithelial …

Temporal stability and composition of the ocular surface microbiome

J Ozkan, S Nielsen, C Diez-Vives, M Coroneo… - Scientific reports, 2017 - nature.com
To determine if there is a core ocular surface microbiome and whether there are microbial
community changes over time, the conjunctiva of 45 healthy subjects were sampled at three …