[HTML][HTML] Amino acid metabolism, transport and signalling in the liver revisited
The liver controls the systemic exposure of amino acids entering via the gastro-intestinal
tract. For most amino acids except branched chain amino acids, hepatic uptake is very …
tract. For most amino acids except branched chain amino acids, hepatic uptake is very …
Harnessing adult-plant resistance genes to deploy durable disease resistance in crops
Adult-plant resistance (APR) is a type of genetic resistance in cereals that is effective during
the later growth stages and can protect plants from a range of disease-causing pathogens …
the later growth stages and can protect plants from a range of disease-causing pathogens …
Quantitative modelling of amino acid transport and homeostasis in mammalian cells
Homeostasis is one of the fundamental concepts in physiology. Despite remarkable
progress in our molecular understanding of amino acid transport, metabolism and signaling …
progress in our molecular understanding of amino acid transport, metabolism and signaling …
Amino acid transporters as modulators of glucose homeostasis
S Bröer - Trends in Endocrinology & Metabolism, 2022 - cell.com
Amino acids modulate glucose homeostasis. Cytosolic levels of amino acids are regulated
by amino acid transporters, modulating insulin release, protein synthesis, cell proliferation …
by amino acid transporters, modulating insulin release, protein synthesis, cell proliferation …
Intestinal amino acid transport and metabolic health
S Bröer - Annual review of nutrition, 2023 - annualreviews.org
Amino acids derived from protein digestion are important nutrients for the growth and
maintenance of organisms. Approximately half of the 20 proteinogenic amino acids can be …
maintenance of organisms. Approximately half of the 20 proteinogenic amino acids can be …
Molecular basis of inhibition of the amino acid transporter B0AT1 (SLC6A19)
J Xu, Z Hu, L Dai, A Yadav, Y Jiang, A Bröer… - Nature …, 2024 - nature.com
The epithelial neutral amino acid transporter B0AT1 (SLC6A19) is the major transporter for
the absorption of neutral amino acids in the intestine and their reabsorption in the kidney …
the absorption of neutral amino acids in the intestine and their reabsorption in the kidney …
The “www” of Xenopus laevis Oocytes: The Why, When, What of Xenopus laevis Oocytes in Membrane Transporters Research
After 50 years, the heterologous expression of proteins in Xenopus laevis oocytes is still
essential in many research fields. New approaches and revised protocols, but also classical …
essential in many research fields. New approaches and revised protocols, but also classical …
Identification and characterization of a novel SNAT2 (SLC38A2) inhibitor reveals synergy with glucose transport inhibition in cancer cells
SNAT2 (SLC38A2) is a sodium-dependent neutral amino acid transporter, which is
important for the accumulation of amino acids as nutrients, the maintenance of cellular …
important for the accumulation of amino acids as nutrients, the maintenance of cellular …
Do amino acid antiporters have asymmetric substrate specificity?
Amino acid antiporters mediate the 1: 1 exchange of groups of amino acids. Whether
substrate specificity can be different for the inward and outward facing conformation has not …
substrate specificity can be different for the inward and outward facing conformation has not …
Deorphanizing solute carriers in Saccharomyces cerevisiae for secondary uptake of xenobiotic compounds
I Møller-Hansen, J Sáez-Sáez… - Frontiers in …, 2024 - frontiersin.org
The exchange of small molecules between the cell and the environment happens through
transporter proteins. Besides nutrients and native metabolic products, xenobiotic molecules …
transporter proteins. Besides nutrients and native metabolic products, xenobiotic molecules …