Corneal blindness is one of the most common causes of vision loss worldwide, affecting
millions of people. To treat these patients, researchers have been examining different …

Gelatin has been used for many years in pharmaceutical formulation, cell culture and tissue
engineering on account of its excellent biocompatibility, ease of processing and availability …

The state of the art therapy for treating corneal endothelial disease is transplantation.
Advances in the reproducibility and accessibility of surgical techniques are increasing the …

Driven by enormous clinical need, myocardial tissue engineering has become a prime focus
of research within the field of tissue engineering. Myocardial tissue engineering combines …

Background: Since the cornea is responsible for transmitting and focusing light into the eye,
injury or pathology affecting any layer of the cornea can cause a detrimental effect on visual …

The monolayer of cells forming the human corneal endothelium is critical to the maintenance
of corneal transparency and is not known to regenerate in vivo. Thus, dysfunction of these …

Biocompatibility is a major requirement for the development of functional biomaterials for
ophthalmic applications. In this study, we investigated the effect of cross-linker functionality …

Tissue engineering of the cornea could overcome shortages of donor corneas for
transplantation and improve quality. Our aim was to grow an endothelial layer on a …

Human corneal endothelium has long been thought to be a nonmitotic cell layer with no
endogenous reparative potential. Pathologies that damage endothelial function result in …

The global shortage of donor corneas has garnered extensive interest in the development of
graft alternatives suitable for endothelial keratoplasty using cultivated primary human …