Neuroinflammation and Neurodegenerative Diseases: How Much Do We Still Not Know?

CR Balistreri, R Monastero - Brain sciences, 2023 - mdpi.com
The term “neuroinflammation” defines the typical inflammatory response of the brain closely
related to the onset of many neurodegenerative diseases (NDs). Neuroinflammation is well …

Recent research trends in Neuroinflammatory and neurodegenerative disorders

J Cohen, A Mathew, KD Dourvetakis… - Cells, 2024 - mdpi.com
Neuroinflammatory and neurodegenerative disorders including Alzheimer's disease (AD),
Parkinson's disease (PD), traumatic brain injury (TBI) and Amyotrophic lateral sclerosis …

Extracellular vesicles from NSC-34 MN-like cells transfected with mutant SOD1 modulate inflammatory status of Raw 264.7 macrophages

E Carata, M Muci, S Mariano, S Di Giulio, A Nigro… - Genes, 2024 - mdpi.com
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease targeting the brain and
spinal cord. Non-neuronal cells, including macrophages, may contribute to the disruption of …

Extracellular vesicles and the immune system: From immunological function to therapeutic application

A Jiang - Immunological investigations, 2024 - Taylor & Francis
Extracellular vesicles (EVs) represent a diverse class of cell-derived membranous structures
that are released by virtually all cell types into the extracellular space. Initially regarded as …

Extracellular vesicles: biological mechanisms and emerging therapeutic opportunities in neurodegenerative diseases

L Wang, X Zhang, Z Yang, B Wang, H Gong… - Translational …, 2024 - Springer
Extracellular vesicles (EVs) are membrane vesicles originating from different cells within the
brain. The pathophysiological role of EVs in neurodegenerative diseases is progressively …

Peripheral extracellular vesicles in neurodegeneration: pathogenic influencers and therapeutic vehicles

X Liu, L Shen, M Wan, H **e, Z Wang - Journal of Nanobiotechnology, 2024 - Springer
Neurodegenerative diseases (NDDs) such as Alzheimer's disease, Parkinson's disease,
and amyotrophic lateral sclerosis epitomize a class of insidious and relentless neurological …

Ultrastructural Characterization of PBMCs and Extracellular Vesicles in Multiple Sclerosis: A Pilot Study

R De Masi, S Orlando, E Carata… - International Journal of …, 2024 - mdpi.com
Growing evidence identifies extracellular vesicles (EVs) as important cell-to-cell signal
transducers in autoimmune disorders, including multiple sclerosis (MS). If the etiology of MS …

A Potential Role of Interleukin-5 in the Pathogenesis and Progression of Amyotrophic Lateral Sclerosis: A New Molecular Perspective

A Moțățăianu, S Andone, A Stoian, R Bălașa… - International Journal of …, 2024 - mdpi.com
Cumulative data suggest that neuroinflammation plays a prominent role in amyotrophic
lateral sclerosis (ALS) pathogenesis. The purpose of this work was to assess if patients with …

The Neuromuscular Disorder Mediated by Extracellular Vesicles in Amyotrophic Lateral Sclerosis

E Carata, M Muci, S Di Giulio, T Di Giulio… - Current Issues in …, 2024 - mdpi.com
Amyotrophic lateral sclerosis (ALS) represents a neurodegenerative disorder characterized
by the progressive loss of both upper and lower motor neurons, resulting in muscular …

Secretome–the role of extracellular vesicles in the pathogenesis and therapy of neurodegenerative diseases

A Sulek - Advances in Psychiatry and Neurology/Postępy …, 2024 - termedia.pl
Purpose: Extracellular vesicles are the subject of many studies in various medical
specialties. Their role in neurodegenerative diseases is increasing and they worth …