Highlights•Fatty acid binding protein 5 (FABP5) is a key regulator of cell metabolism and
growth that is overexpressed in cancers.•FABP5 facilitates the activation of transcriptional …

RNA interference (RNAi) is an endogenous post-transcriptional gene regulatory mechanism,
where non-coding, double-stranded RNA molecules interfere with the expression of certain …

One of the most importantly involved pathways in cancer development is fatty-acid signaling
pathway. Synthesized lipids as energetic sources are consumed by cancer cells for …

Recent studies using animal models suggest that expression of FABP5 drives the
stimulation of cell growth observed in estrogen receptor (ER)-negative breast cancer cells …

Highlights•Fatty acid binding protein 5 (FABP5) is upregulated in many cancers, particularly
prostate cancer (PC).•FABP5 facilitates the delivery of fatty acids to peroxisome proliferator …

Prostate cancer (PCa) is the most commonly diagnosed cancer in males in the Western
world. Although prostate-specific antigen (PSA) has been widely used as a biomarker for …

In previous work, it is suggested that the excessive amount of fatty acids transported by
FABP5 may facilitate the malignant progression of prostate cancer cells through a FABP5 …

Early stage localized prostate cancer (PCa) has an excellent prognosis; however, patient
survival drops dramatically when PCa metastasizes. The molecular mechanisms underlying …

FABP7 has been implicated in tumour cell proliferation, cell migration, and poor prognosis in
patients with high‐grade astrocytoma and melanoma. In this study, we examine FABP7 …

Despite great progress in the detection and treatment of prostate cancer, this disease
remains an incredible health and economic burden. Although androgen receptor (AR) …