Abstract The Food and Drug Administration (FDA) regulates pharmaceutical drug products
to ensure a continuous supply of high-quality drugs in the USA. Continuous processing has …

Recently, the pharmaceutical industry has been facing several challenges associated to the
use of outdated development and manufacturing technologies. The return on investment on …

The entire pharmaceutical sector is in an urgent need of both innovative technological
solutions and fundamental scientific work, enabling the production of highly engineered …

This scientific paper presents an overview of continuous solution crystallization in the
pharmaceutical industry. Since the specific knowledge spectrum of precipitation is very …

Abstract The Quality-by-Design (QbD) guidance issued by the US Food and Drug
Administration (FDA) has catalyzed the modernization of pharmaceutical manufacturing …

The pharmaceutical industry has found new applications for the use of continuous
processing for the manufacture of new therapies currently in development. The …

While machine learning (ML) has made significant contributions to the biopharmaceutical
field, its applications are still in the early stages in terms of providing direct support for quality …

Continuous crystallization has gained interest in the pharmaceutical sector as part of the
drive toward the transition from exclusive batch manufacturing to integrated continuous …

Industrial-scale bioprocessing underpins much of the production of pharmaceuticals,
nutraceuticals, food, and beverage processing industries of the modern world. The …

This article provides a perspective on control and operations for biopharmaceutical
manufacturing. Challenges and opportunities are described for (1) microscale technologies …