Volatile organic compounds in exhaled breath as fingerprints of lung cancer, asthma and COPD

IA Ratiu, T Ligor, V Bocos-Bintintan… - Journal of clinical …, 2020 - mdpi.com
Lung cancer, chronic obstructive pulmonary disease (COPD) and asthma are inflammatory
diseases that have risen worldwide, posing a major public health issue, encompassing not …

On-Line Analysis of Exhaled Breath: Focus Review

T Bruderer, T Gaisl, MT Gaugg, N Nowak… - Chemical …, 2019 - ACS Publications
On-line analysis of exhaled breath offers insight into a person's metabolism without the need
for sample preparation or sample collection. Due to its noninvasive nature and the possibility …

Breath analysis: a promising tool for disease diagnosis—the role of sensors

M Kaloumenou, E Skotadis, N Lagopati… - Sensors, 2022 - mdpi.com
Early-stage disease diagnosis is of particular importance for effective patient identification as
well as their treatment. Lack of patient compliance for the existing diagnostic methods …

Exhaled breath analysis: a review of 'breath-taking'methods for off-line analysis

O Lawal, WM Ahmed, TME Nijsen, R Goodacre… - Metabolomics, 2017 - Springer
Background The potential of exhaled breath sampling and analysis has long attracted
interest in the areas of medical diagnosis and disease monitoring. This interest is attributed …

Asthma endotypes and an overview of targeted therapy for asthma

S Svenningsen, P Nair - Frontiers in medicine, 2017 - frontiersin.org
Guidelines for the management of severe asthma do not emphasize the measurement of the
inflammatory component of airway disease to indicate appropriate treatments or to monitor …

Evidence for widespread human exposure to food contact chemicals

B Geueke, LV Parkinson, KJ Groh… - Journal of Exposure …, 2024 - nature.com
Background Over 1800 food contact chemicals (FCCs) are known to migrate from food
contact articles used to store, process, package, and serve foodstuffs. Many of these FCCs …

Fevipiprant, a prostaglandin D2 receptor 2 antagonist, in patients with persistent eosinophilic asthma: a single-centre, randomised, double-blind, parallel-group …

S Gonem, R Berair, A Singapuri, R Hartley… - The Lancet …, 2016 - thelancet.com
Background Eosinophilic airway inflammation is often present in asthma, and reduction of
such inflammation results in improved clinical outcomes. We hypothesised that fevipiprant …

Diagnosis of COVID-19 by exhaled breath analysis using gas chromatography–mass spectrometry

W Ibrahim, RL Cordell, MJ Wilde… - ERJ open …, 2021 - Eur Respiratory Soc
Background The ongoing coronavirus disease 2019 (COVID-19) pandemic has claimed
over two and a half million lives worldwide so far. Severe acute respiratory syndrome …

Pathophysiological mechanisms of asthma

A Bush - Frontiers in pediatrics, 2019 - frontiersin.org
The recent Lancet commission has highlighted that “asthma” should be used to describe a
clinical syndrome of wheeze, breathlessness, chest tightness, and sometimes cough. The …

Exhaled volatile organic compounds are able to discriminate between neutrophilic and eosinophilic asthma

FN Schleich, D Zanella, PH Stefanuto… - American journal of …, 2019 - atsjournals.org
Rationale: Analysis of exhaled breath for asthma phenoty** using endogenously
generated volatile organic compounds (VOCs) offers the possibility of noninvasive diagnosis …