Synthetic biology applies genetic tools to engineer living cells and organisms analogous to
the programming of machines. In materials synthetic biology, engineering principles from …

Molecular data storage is an attractive alternative for dense and durable information storage,
which is sorely needed to deal with the growing gap between information production and the …

Single-cell transcriptomics (scRNA-seq) has greatly advanced our ability to characterize
cellular heterogeneity. However, scRNA-seq requires lysing cells, which impedes further …

Synthetic biology is driving a new era of medicine through the genetic programming of living
cells,. This transformative approach allows for the creation of engineered systems that …

Cellular processes are carried out by many genes, and their study and optimization requires
multiple levers by which they can be independently controlled. The most common method is …

Our ability to generate bacterial strains with unique and increasingly complex functions has
rapidly expanded in recent times. The capacity for DNA synthesis is increasing and costing …

Efforts to construct synthetic networks in living cells have been hindered by the limited
number of regulatory components that provide wide dynamic range and low crosstalk. Here …

The ability to rationally engineer microorganisms has been a long-envisioned goal dating
back more than a half-century. With the genomics revolution and rise of systems biology in …

Cells navigate environments, communicate and build complex patterns by initiating gene
expression in response to specific signals. Engineers seek to harness this capability to …

Molecular circuits capable of processing temporal information are essential for complex
decision making in response to both the presence and history of a molecular environment. A …