The human preterm brain is particularly susceptible to cerebral white matter injury (WMI) that
disrupts the normal progression of developmental myelination. Advances in the care of …

Neonatal hypoxia-ischaemia (HI) is the most common cause of death and disability in
human neonates, and is often associated with persistent motor, sensory, and cognitive …

The many recent discoveries concerning the molecular biologic bases of malformations of
cortical development and the discovery of new such malformations have rendered previous …

White matter damage (WMD) in preterm neonates is strongly associated with adverse
outcome. The etiology of white matter injury is not known but clinical data suggest that …

Objective: Activated microglia play a central role in the inflammatory and excitotoxic
component of various acute and chronic neurological disorders. However, the mechanisms …

Microglial cells penetrate into and scatter throughout the human cortical grey and white
matter according to a specific spatiotemporal pattern during the first 2 trimesters of gestation …

This article is focused on the mechanisms underlying primarily ischaemic/reperfusion brain
injury in both the term and premature infant. Although the mechanisms involved include …

Injury to the preterm brain has a particular predilection for cerebral white matter. White
matter injury (WMI) is the most common cause of brain injury in preterm infants and a major …

The inflammatory response triggered by stroke has been viewed as harmful, focusing on the
influx and migration of blood-borne leukocytes, neutrophils, and macrophages. This review …

Despite advances in neonatal intensive care, survivors of premature birth remain highly
susceptible to unique patterns of developmental brain injury that manifest as cerebral palsy …