Ageing is characterized by the functional decline of tissues and organs and the increased
risk of ageing-associated disorders. Several 'rejuvenating'interventions have been proposed …

Access to DNA is a prerequisite to the execution of essential cellular processes that include
transcription, replication, chromosomal segregation, and DNA repair. How the proteins that …

The first major developmental transition in vertebrate embryos is the maternal-to-zygotic
transition (MZT) when maternal mRNAs are degraded and zygotic transcription begins …

Craniofacial anomalies are among the most common of birth defects. The pathogenesis of
craniofacial anomalies frequently involves defects in the migration, proliferation, and fate of …

Cell senescence, which is an irreversible state of cell proliferative arrest, has emerged as a
potentially important contributor to tissue dysfunction and organismal ageing. Cell …

The rate of substance use is rising, especially among reproductive-age individuals.
Emerging evidence suggests that paternal pre-conception and maternal prenatal substance …

Epigenetic regulation, notably histone post-translational modification (PTM), has emerged
as a major transcriptional control of gene expression during cellular stress adaptation. In the …

Introduction Zinc oxide nanoparticles (ZnO NPs) show anti-cancer activity. Diffuse Large B-
cell Lymphoma (DLBCL) is a type of B-cell malignancies with unsatisfying treatment …

The goldenrod gall fly (Eurosta solidaginis) is a well-studied model of insect freeze
tolerance. In situations of prolonged winter subzero temperatures, larvae of E. solidaginis …

The advance of replication forks to duplicate chromosomes in dividing cells requires the
disassembly of nucleosomes ahead of the fork and the rapid assembly of parental and de …