Locomotion results from complex interactions between the central nervous system and the
musculoskeletal system with its many degrees of freedom and muscles. Gaining insight into …

Abstract Changes in old age that contribute to the complex issue of an increased metabolic
cost of walking (mass-specific energy cost per unit distance traveled) in older adults appear …

Musculoskeletal simulations are used in many different applications, ranging from the
design of wearable robots that interact with humans to the analysis of patients with impaired …

Accurate predictive simulations of human gait rely on optimisation criteria to solve the
system's redundancy. Defining such criteria is challenging, as the objectives driving the …

Over the past decade, there has been a rapid increase in applications of multibody system
dynamics to the predictive simulation of human movement. Using predictive “what-if” human …

The ultimate goal of most neuromusculoskeletal modeling research is to improve the
treatment of movement impairments. However, even though neuromusculoskeletal models …

This letter presents a novel method for reference trajectory adaptation in lower limb
rehabilitation exoskeletons during walking. Our adaptation rule is extracted from a cost …

Trajectory optimization with musculoskeletal models can be used to reconstruct measured
movements and to predict changes in movements in response to environmental changes. It …

The direct collocation (DC) method has shown low computational costs in solving
optimization problems in human movements, but it has rarely been used for solving optimal …

Lower limb exoskeletons serve multiple purposes, like supporting and augmenting
movement. Biomechanical models are practical tools to understand human movement, and …