[HTML][HTML] Brain malignancies: Glioblastoma and brain metastases

TT Lah, M Novak, B Breznik - Seminars in cancer biology, 2020 - Elsevier
Brain, the major organ of the central nervous system controls and processes most of body
activities. Therefore, the most aggressive brain tumor–glioblastoma and metastases from …

[HTML][HTML] Effect of stromal cells in tumor microenvironment on metastasis initiation

S Guo, CX Deng - International journal of biological sciences, 2018 - ncbi.nlm.nih.gov
The cellular environment where tumor cells reside is called the tumor microenvironment
(TME), which consists of borders, blood vessels, lymph vessels, extracellular matrix (ECM) …

Cannabigerol is a potential therapeutic agent in a novel combined therapy for glioblastoma

TT Lah, M Novak, MA Pena Almidon, O Marinelli… - Cells, 2021 - mdpi.com
Simple Summary Among primary brain tumours, glioblastoma is the most aggressive. As
early relapses are unavoidable despite standard-of-care treatment, the cannabinoids delta-9 …

[HTML][HTML] Angiogenesis in gynecological cancers and the options for anti-angiogenesis therapy

B Yetkin-Arik, AW Kastelein, I Klaassen… - … et Biophysica Acta (BBA …, 2021 - Elsevier
Angiogenesis is required in cancer, including gynecological cancers, for the growth of
primary tumors and secondary metastases. Development of anti-angiogenesis therapy in …

[HTML][HTML] In vitro biomimetic models for glioblastoma-a promising tool for drug response studies

T Stanković, T Ranđelović, M Dragoj, SS Burić… - Drug Resistance …, 2021 - Elsevier
The poor response of glioblastoma to current treatment protocols is a consequence of its
intrinsic drug resistance. Resistance to chemotherapy is primarily associated with …

Current status and potential challenges of mesenchymal stem cell-based therapy for malignant gliomas

Q Zhang, W **ang, D Yi, B Xue, W Wen… - Stem Cell Research & …, 2018 - Springer
Glioma, which accounts for more than 30% of primary central nervous system tumours, is
characterised by symptoms such as headaches, epilepsy, and blurred vision. Glioblastoma …

NADPH oxidase subunit CYBB confers chemotherapy and ferroptosis resistance in mesenchymal glioblastoma via nrf2/SOD2 modulation

IC Su, YK Su, SA Setiawan, VK Yadav, IH Fong… - International journal of …, 2023 - mdpi.com
Glioblastoma multiforme (GBM) is a highly heterogeneous disease with a mesenchymal
subtype tending to exhibit more aggressive and multitherapy-resistant features …

Infiltrating natural killer cells bind, lyse and increase chemotherapy efficacy in glioblastoma stem-like tumorospheres

B Breznik, MW Ko, C Tse, PC Chen, E Senjor… - Communications …, 2022 - nature.com
Glioblastomas remain the most lethal primary brain tumors. Natural killer (NK) cell-based
therapy is a promising immunotherapeutic strategy in the treatment of glioblastomas, since …

[HTML][HTML] Mesenchymal stem cells in glioblastoma therapy and progression: How one cell does it all

B Nowak, P Rogujski, M Janowski, B Lukomska… - … et Biophysica Acta (BBA …, 2021 - Elsevier
Mesenchymal stem cells (MSCs) are among the most investigated and applied somatic stem
cells in experimental therapies for the regeneration of damaged tissues. Moreover, as it was …

[HTML][HTML] Brain tumor networks in diffuse glioma

Y Yang, MC Schubert, T Kuner, W Wick, F Winkler… - …, 2022 - Elsevier
Diffuse gliomas are primary brain tumors associated with a poor prognosis. Cellular and
molecular mechanisms driving the invasive growth patterns and therapeutic resistance are …