Micro total analysis systems: fundamental advances and applications in the laboratory, clinic, and field

ML Kovarik, DM Ornoff, AT Melvin, NC Dobes… - Analytical …, 2013 - ACS Publications
Assay devices designed for these applications offer improvements to existing methods or
provide fundamentally new strategies. Both mature methods and novel techniques have …

Application of microfluidic technologies to human assisted reproduction

GD Smith, S Takayama - MHR: Basic science of reproductive …, 2017 - academic.oup.com
Microfluidics can be considered both a science and a technology. It is defined as the study of
fluid behavior at a sub-microliter level and the investigation into its application to cell …

The future of IVF: the new normal in human reproduction

VA Kushnir, GD Smith, EY Adashi - Reproductive Sciences, 2022 - Springer
Increased demand for in vitro fertilization (IVF) due to socio-demographic trends, and supply
facilitated by new technologies, converged to transform the way a substantial proportion of …

Advanced cryopreservation as an emergent and convergent technological platform

E Brister, PB Thompson, SM Wolf, JC Bischof - Technology in Society, 2024 - Elsevier
Advanced cryopreservation technologies have the potential to transform organ transplants,
biomedical research, food storage, aquaculture, biodiversity repositories, ecological …

Advanced technologies for the preservation of mammalian biospecimens

H Huang, X He, ML Yarmush - Nature biomedical engineering, 2021 - nature.com
The three classical core technologies for the preservation of live mammalian biospecimens—
slow freezing, vitrification and hypothermic storage—limit the biomedical applications of …

Microfluidics for cryopreservation

G Zhao, J Fu - Biotechnology advances, 2017 - Elsevier
Cryopreservation has utility in clinical and scientific research but implementation is highly
complex and includes labor-intensive cell-specific protocols for the addition/removal of …

Advances in microfluidics‐based assisted reproductive technology: From sperm sorter to reproductive system‐on‐a‐chip

N Kashaninejad, MJA Shiddiky… - Advanced …, 2018 - Wiley Online Library
The fields of assisted reproductive technology (ART) and in vitro fertilization (IVF) have
progressed rapidly, yet still need further improvements. Microfluidic technology can …

Microfluidic in-vitro fertilization technologies: Transforming the future of human reproduction

Y Fang, R Wu, JM Lee, LHM Chan, KYJ Chan - TrAC Trends in Analytical …, 2023 - Elsevier
The field of assisted reproductive technology (ART) has seen constant improvement and
advancement targeted towards optimal development of the embryos in vitro to improve …

Thinking big by thinking small: application of microfluidic technology to improve ART

JE Swain, D Lai, S Takayama, GD Smith - Lab on a Chip, 2013 - pubs.rsc.org
In Vitro Fertilization (IVF) laboratories often carry a penchant to resist change while in the
pursuit of maintaining consistency in laboratory conditions. However, implementation of new …

Cryopreservation in the era of cell therapy: revisiting fundamental concepts to enable future technologies

B Bai, C Xue, Y Wen, J Lim, Z Le… - Advanced Functional …, 2023 - Wiley Online Library
Cryopreservation strives to maximize the viability and biofunctionality of cells and tissues by
cooling them to a subzero temperature to facilitate storage and delivery. This technology has …