Protein post-translational modification (PTM) is a covalent process that occurs in proteins
during or after translation through the addition or removal of one or more functional groups …

Infectious diseases, along with cancers, are among the main causes of death among
humans worldwide. The production of therapeutic proteins for treating diseases at large …

The biopharmaceutical market has experienced a tremendous growth in the last years.
However, this growth should be balanced considering the difficulty in bioproduct …

This review is the tenth update of the original article published in 1999 on the application of
matrix‐assisted laser desorption/ionization (MALDI) mass spectrometry to the analysis of …

Minor changes in the quality of biologically manufactured monoclonal antibodies (mAbs)
can affect their bioactivity and efficacy. One of the most important variations concerns the N …

Describing advances relevant to the field of bioprocess intensification (BI) in particular is a
challenge for several reasons. Digital biomanufacturing can support both advanced …

Biochemistry and structural biology have benefited tremendously from the development of
electrospray ionization and matrix-assisted laser desorption/ionization, the two most …

Online monitoring of monoclonal antibody (mAb) product titers throughout biologics process
development and production enables the implementation of quality-by-design …