The idea that epigenetic determinants such as DNA methylation, histone modifications or
RNA can be passed to the next generation through meiotic products (gametes) is long …

Research efforts during the past decades have provided intriguing evidence suggesting that
stressful experiences during pregnancy exert long-term consequences on the future mental …

Using olfactory molecular specificity, we examined the inheritance of parental traumatic
exposure, a phenomenon that has been frequently observed, but not understood. We …

Chromatin, the physiological template of all eukaryotic genetic information, is subject to a
diverse array of posttranslational modifications that largely im**e on histone amino …

The character of a cell is defined by its constituent proteins, which are the result of specific
patterns of gene expression. Crucial determinants of gene expression patterns are DNA …

Chromatin modifiers regulate lifespan in several organisms, raising the question of whether
changes in chromatin states in the parental generation could be incompletely …

The decline in hematopoietic function seen during aging involves a progressive reduction in
the immune response and an increased incidence of myeloid malignancy, and has been …

Polycomb group (PcG) proteins maintain transcriptional repression during development,
likely by creating repressive chromatin states. The Extra Sex Combs (ESC) and Enhancer of …

Enhancer of Zeste is a Polycomb Group protein essential for the establishment and
maintenance of repression of homeotic and other genes. In the early embryo it is found in a …

Regulatory T (Treg) cells, whose identity and function are defined by the transcription factor
Foxp3, are indispensable for immune homeostasis. It is unclear whether Foxp3 exerts its …