Hyperelastic energy densities for soft biological tissues: a review

G Chagnon, M Rebouah, D Favier - Journal of Elasticity, 2015 - Springer
Many soft tissues are naturally made of a matrix and fibres that present some privileged
directions. They are known to support large reversible deformations. The mechanical …

Heart valve macro-and microstructure

M Misfeld, HH Sievers - … of the Royal Society B: Biological …, 2007 - royalsocietypublishing.org
Each heart valve is composed of different structures of which each one has its own
histological profile. Although the aortic and the pulmonary valves as well as the mitral and …

An investigation of the anisotropic mechanical properties and anatomical structure of porcine atrioventricular heart valves

S Jett, D Laurence, R Kunkel, AR Babu… - Journal of the …, 2018 - Elsevier
Valvular heart diseases are complex disorders, varying in pathophysiological mechanism
and affected valve components. Understanding the effects of these diseases on valve …

Computational modeling of cardiac valve function and intervention

W Sun, C Martin, T Pham - Annual review of biomedical …, 2014 - annualreviews.org
In the past two decades, major advances have been made in the clinical evaluation and
treatment of valvular heart disease owing to the advent of noninvasive cardiac imaging …

[BOOK][B] Vortex formation in the heart

A Kheradvar, G Pedrizzetti, A Kheradvar, G Pedrizzetti - 2012 - Springer
The presence of vortical flow structures that develop inside different cardiac chambers is
shown to correlate with functional status of heart, and significantly affects the cardiac …

Transforming growth factor-β regulates in vitro heart valve repair by activated valve interstitial cells

AC Liu, AI Gotlieb - The American journal of pathology, 2008 - Elsevier
The regulation of valve interstitial cell (VIC) function in response to tissue injury and valve
disease is not well understood. Because transforming growth factor-β (TGF-β) has been …

A noninvasive method for the determination of in vivo mitral valve leaflet strains

BV Rego, AH Khalighi, A Drach, EK Lai… - … journal for numerical …, 2018 - Wiley Online Library
Assessment of mitral valve (MV) function is important in many diagnostic, prognostic, and
surgical planning applications for treatment of MV disease. Yet, to date, there are no …

Material properties of the ovine mitral valve anterior leaflet in vivo from inverse finite element analysis

G Krishnamurthy, DB Ennis, A Itoh… - American Journal …, 2008 - journals.physiology.org
We measured leaflet displacements and used inverse finite-element analysis to define, for
the first time, the material properties of mitral valve (MV) leaflets in vivo. Sixteen miniature …

Development of a functionally equivalent model of the mitral valve chordae tendineae through topology optimization

AH Khalighi, BV Rego, A Drach, RC Gorman… - Annals of biomedical …, 2019 - Springer
Ischemic mitral regurgitation (IMR) is a currently prevalent disease in the US that is projected
to become increasingly common as the aging population grows. In recent years, image …

Material properties of aged human mitral valve leaflets

T Pham, W Sun - Journal of biomedical materials research Part …, 2014 - Wiley Online Library
This study aimed to characterize the mechanical properties of aged human anterior mitral
leaflets (AML) and posterior mitral leaflets (PML). The AML and PML samples from …