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Genome editing and bioinformatics
Bioinformatics has become an indispensable technology in molecular biology for genome
editing. In this review, we outline various bioinformatic techniques necessary for genome …
editing. In this review, we outline various bioinformatic techniques necessary for genome …
Microbial cell factories in the bioeconomy era: from discovery to creation
X Yan, Q He, B Geng, S Yang - BioDesign Research, 2024 - spj.science.org
Microbial cell factories (MCFs) are extensively used to produce a wide array of bioproducts,
such as bioenergy, biochemical, food, nutrients, and pharmaceuticals, and have been …
such as bioenergy, biochemical, food, nutrients, and pharmaceuticals, and have been …
Crabtree/Warburg-like aerobic xylose fermentation by engineered Saccharomyces cerevisiae
SB Lee, M Tremaine, M Place, L Liu, A Pier… - Metabolic …, 2021 - Elsevier
Bottlenecks in the efficient conversion of xylose into cost-effective biofuels have limited the
widespread use of plant lignocellulose as a renewable feedstock. The yeast Saccharomyces …
widespread use of plant lignocellulose as a renewable feedstock. The yeast Saccharomyces …
Oxygenation influences xylose fermentation and gene expression in the yeast genera Spathaspora and Scheffersomyces
Background Cost-effective production of biofuels from lignocellulose requires the
fermentation of d-xylose. Many yeast species within and closely related to the genera …
fermentation of d-xylose. Many yeast species within and closely related to the genera …
Ploidy evolution in a wild yeast is linked to an interaction between cell type and metabolism
Ploidy is an evolutionarily labile trait, and its variation across the tree of life has profound
impacts on evolutionary trajectories and life histories. The immediate consequences and …
impacts on evolutionary trajectories and life histories. The immediate consequences and …
Comparative functional genomics identifies an iron-limited bottleneck in a Saccharomyces cerevisiae strain with a cytosolic-localized isobutanol pathway
FV Gambacorta, ER Wagner, TB Jacobson… - Synthetic and Systems …, 2022 - Elsevier
Metabolic engineering strategies have been successfully implemented to improve the
production of isobutanol, a next-generation biofuel, in Saccharomyces cerevisiae. Here, we …
production of isobutanol, a next-generation biofuel, in Saccharomyces cerevisiae. Here, we …
Combinatorial library design for improving isobutanol production in Saccharomyces cerevisiae
FV Gambacorta, JJ Dietrich, JJ Baerwald… - … in Bioengineering and …, 2022 - frontiersin.org
Saccharomyces cerevisiae is the dominant fermentative producer of ethanol in industry and
a preferred host for production of other biofuels. That said, rewiring the metabolism of S …
a preferred host for production of other biofuels. That said, rewiring the metabolism of S …
Revitalizing the ethanologenic bacterium Zymomonas mobilis for sugar reduction in high-sugar-content fruits and commercial products
M Hu, X Chen, J Huang, J Du, M Li, S Yang - Bioresources and …, 2021 - Springer
The excessive consumption of sugars can cause health issues. Different strategies have
been developed to reduce sugars in the diets. However, sugars in fruits and commercial …
been developed to reduce sugars in the diets. However, sugars in fruits and commercial …
The Evolution of Nucleic Acid–Based Diagnosis Methods from the (pre-) CRISPR to CRISPR era and the Associated Machine/Deep Learning Approaches in Relevant …
Nucleic acid tests (NATs) are considered as gold standard in molecular diagnosis. To meet
the demand for onsite, point-of-care, specific and sensitive, trace and genotype detection of …
the demand for onsite, point-of-care, specific and sensitive, trace and genotype detection of …
[HTML][HTML] Improved vectors for retron-mediated CRISPR-Cas9 genome editing in Saccharomyces cerevisiae
TN Stuecker, SE Hood, JM Pineda, S Lenaduwe… - …, 2024 - pmc.ncbi.nlm.nih.gov
In vivo site-directed mutagenesis is a powerful genetic tool for testing the effects of specific
alleles in their normal genomic context. While the budding yeast Saccharomyces cerevisiae …
alleles in their normal genomic context. While the budding yeast Saccharomyces cerevisiae …