Interpretable artificial intelligence and exascale molecular dynamics simulations to reveal kinetics: Applications to Alzheimer's disease

W Martin, G Sheynkman, FC Lightstone… - Current opinion in …, 2022 - Elsevier
The rapid increase in computing power, especially with the integration of graphics
processing units, has dramatically increased the capabilities of molecular dynamics …

Novel therapeutic target for prevention of neurodegenerative diseases: modulation of neuroinflammation with Sig-1R ligands

F Bogár, L Fülöp, B Penke - Biomolecules, 2022 - mdpi.com
Neurodegenerative diseases (NDDs) are characterized by progressive deterioration of the
structure and function of cells and their networks in the nervous system. There are currently …

Antiviral immune response in Alzheimer's disease: Connecting the dots

ER Roy, W Cao - Frontiers in Neuroscience, 2020 - frontiersin.org
Alzheimer's disease (AD) represents an enormous public health challenge currently and
with increasing urgency in the coming decades. Our understanding of the etiology and …

[PDF][PDF] Novel therapeutic target for prevention of neurodegenerative diseases: modulation of neuroinflammation with Sig-1R ligands. Biomolecules. 2022; 12 (3): 363

F Bogár, L Fülöp, B Penke - PubMed CrossRef Show Abstract, 2022 - academia.edu
Neurodegenerative diseases (NDDs) are characterized by progressive deterioration of the
structure and function of cells and their networks in the nervous system. There are currently …

Regulation of microglial surveillance and phagocytosis in health and disease

P Izquierdo Garrudo - 2021 - discovery.ucl.ac.uk
Microglia are the resident immune cells of the central nervous system. They survey the brain
for redundant synapses, debris and dying cells, which they remove through phagocytosis …