Saffron bioactives crocin, crocetin and safranal: Effect on oxidative stress and mechanisms of action

D Cerdá-Bernad, E Valero-Cases… - Critical reviews in …, 2022 - Taylor & Francis
Saffron (Crocus sativus L.) is used as a spice for its organoleptic characteristics related to its
coloring and flavoring properties, and it has been also used in traditional medicine to treat …

[HTML][HTML] Saffron (Crocus sativus L.): A Source of Nutrients for Health and for the Treatment of Neuropsychiatric and Age-Related Diseases

A El Midaoui, I Ghzaiel, D Vervandier-Fasseur, M Ksila… - Nutrients, 2022 - mdpi.com
Saffron (Crocus sativus L.) is a medicinal plant, originally cultivated in the East and Middle
East, and later in some Mediterranean countries. Saffron is obtained from the stigmas of the …

Crocin: Functional characteristics, extraction, food applications and efficacy against brain related disorders

A Ali, L Yu, S Kousar, W Khalid, Z Maqbool… - Frontiers in …, 2022 - frontiersin.org
Crocin is a bioactive compound that naturally occurs in some medicinal plants, especially
saffron and gardenia fruit. Different conventional and novel methods are used for its …

Crocetin: a systematic review

ZL Guo, MX Li, XL Li, P Wang, WG Wang… - Frontiers in …, 2022 - frontiersin.org
Crocetin is an aglycone of crocin naturally occurring in saffron and produced in biological
systems by hydrolysis of crocin as a bioactive metabolite. It is known to exist in several …

[HTML][HTML] Crocetin prolongs recovery period of DSS-induced colitis via altering intestinal microbiome and increasing intestinal permeability

P Feng, Q Li, L Liu, S Wang, Z Wu, Y Tao… - International journal of …, 2022 - mdpi.com
Crocetin is one of the major active constituents of saffron (Crocus sativus L.) which has a
reputation for facilitating blood circulation and dispersing blood stasis in traditional Chinese …

Role of phytochemicals as nutraceuticals for cognitive functions affected in ageing

MJR Howes, NSL Perry… - British journal of …, 2020 - Wiley Online Library
Cognitive decline can occur with normal ageing and in age‐related brain disorders, such as
mild cognitive impairment and dementia, including Alzheimer's disease, with limited …

[HTML][HTML] Searching for the antioxidant, anti-inflammatory, and neuroprotective potential of natural food and nutritional supplements for ocular health in the …

M Valero-Vello, C Peris-Martínez, JJ García-Medina… - Foods, 2021 - mdpi.com
Adherence to a healthy diet offers a valuable intervention to compete against the increasing
cases of ocular diseases worldwide, such as dry eye disorders, myopia progression …

[HTML][HTML] Natural compounds in glioblastoma therapy: Preclinical insights, mechanistic pathways, and outlook

K Zhai, M Siddiqui, B Abdellatif, A Liskova, P Kubatka… - Cancers, 2021 - mdpi.com
Simple Summary Glioblastoma (GBM) is a tumor of the brain or spinal cord with poor clinical
prognosis. Current interventions, such as chemotherapy and surgical tumor resection, are …

Saffron and its active ingredients against human disorders: A literature review on existing clinical evidence

SF Omidkhoda… - Iranian Journal of Basic …, 2022 - pmc.ncbi.nlm.nih.gov
Saffron, the stigmas of Crocus sativus L., has been mentioned extensively in the traditional
reference texts as a herbal medicine. Many clinical trials have been conducted on this …

Dietary carotenoids to improve hypertension

F Abbasian, MS Alavi, A Roohbakhsh - Heliyon, 2023 - cell.com
Hypertension is one of the major risk factors for cardiovascular diseases and the main
reason for premature death in older adults. Although antihypertensive medications have …