At the interface of sensory and motor dysfunctions and Alzheimer's disease

MW Albers, GC Gilmore, J Kaye, C Murphy… - Alzheimer's & …, 2015 - Elsevier
Recent evidence indicates that sensory and motor changes may precede the cognitive
symptoms of Alzheimer's disease (AD) by several years and may signify increased risk of …

Improving our understanding, and detection, of glaucomatous damage: an approach based upon optical coherence tomography (OCT)

DC Hood - Progress in retinal and eye research, 2017 - Elsevier
Although ophthalmologists are becoming increasingly reliant upon optical coherence
tomography (OCT), clinicians who care for glaucoma patients are not taking full advantage …

Development and validation of a deep learning system to detect glaucomatous optic neuropathy using fundus photographs

H Liu, L Li, IM Wormstone, C Qiao, C Zhang… - JAMA …, 2019 - jamanetwork.com
Importance A deep learning system (DLS) that could automatically detect glaucomatous
optic neuropathy (GON) with high sensitivity and specificity could expedite screening for …

Efficacy of a deep learning system for detecting glaucomatous optic neuropathy based on color fundus photographs

Z Li, Y He, S Keel, W Meng, RT Chang, M He - Ophthalmology, 2018 - Elsevier
Purpose To assess the performance of a deep learning algorithm for detecting referable
glaucomatous optic neuropathy (GON) based on color fundus photographs. Design A deep …

Glaucoma: the retina and beyond

BM Davis, L Crawley, M Pahlitzsch, F Javaid… - Acta …, 2016 - Springer
Over 60 million people worldwide are diagnosed with glaucomatous optic neuropathy,
which is estimated to be responsible for 8.4 million cases of irreversible blindness globally …

Projection-resolved optical coherence tomography angiography of macular retinal circulation in glaucoma

HL Takusagawa, L Liu, KN Ma, Y Jia, SS Gao, M Zhang… - Ophthalmology, 2017 - Elsevier
Purpose To detect macular perfusion defects in glaucoma using projection-resolved optical
coherence tomography (OCT) angiography. Design Prospective observation study …

Detecting glaucoma with only OCT: Implications for the clinic, research, screening, and AI development

DC Hood, S La Bruna, E Tsamis, KA Thakoor… - Progress in Retinal and …, 2022 - Elsevier
A method for detecting glaucoma based only on optical coherence tomography (OCT) is of
potential value for routine clinical decisions, for inclusion criteria for research studies and …

Detecting structural progression in glaucoma with optical coherence tomography

AJ Tatham, FA Medeiros - Ophthalmology, 2017 - Elsevier
Optical coherence tomography (OCT) is increasingly used to obtain objective measurements
of the retinal nerve fiber layer (RNFL), optic nerve head, and macula for assessing glaucoma …

Estimating optical coherence tomography structural measurement floors to improve detection of progression in advanced glaucoma

C Bowd, LM Zangwill, RN Weinreb, FA Medeiros… - American journal of …, 2017 - Elsevier
Purpose “Floor effects” in retinal imaging are defined as the points at which no further
structural loss can be detected. We estimated the measurement floors for spectral-domain …

24-2 visual fields miss central defects shown on 10-2 tests in glaucoma suspects, ocular hypertensives, and early glaucoma

CG De Moraes, DC Hood, A Thenappan, CA Girkin… - Ophthalmology, 2017 - Elsevier
Purpose To investigate the prevalence of visual field defects in glaucomatous eyes,
glaucoma suspects, and ocular hypertensives with 24-2 and 10-2 visual fields. Design …