On December 12, 2019 a new coronavirus (SARS-CoV-2) emerged in Wuhan, China,
triggering a pandemic of severe acute respiratory syndrome in humans (COVID-19). Today …

Obesity is a complex disorder of excessive adiposity, and is associated with adverse health
effects such as cardiometabolic complications, which are to a large extent attributable to …

Group-2 innate lymphoid cells (ILC2), type-2 cytokines, and eosinophils have all been
implicated in sustaining adipose tissue homeostasis. However, the interplay between the …

Excessive visceral fat accumulation is a primary risk factor for metabolically unhealthy
obesity and related diseases. The visceral fat is highly susceptible to the availability of …

Obesity is associated with chronic low-grade white adipose tissue (WAT) inflammation that
can contribute to the development of insulin resistance in mammals. Previous studies have …

We must better understand baseline and perturbed immune health in obese children to
determine how to account for altered frequency and function of humoral and cellular immune …

Obesity and associated metabolic co-morbidities are a worldwide public health problem.
Negative health outcomes associated with obesity, however, do not arise from excessive …

Immoderate calorie intake coupled with a sedentary lifestyle are major determinants of
health issues and inflammatory diseases in modern society. The balance between energy …

The need for efficient and safe therapy to improve such metabolic diseases as obesity and
type 2 diabetes mellitus is currently unmet. The development of dual GIPR–GLP1R …

Over the past decade, the gut microbiome has been linked to several diseases including
gastrointestinal diseases, cancer, immune disorder and metabolic syndrome. Shifts in the …