Gastric cancer in the era of epigenetics

G Christodoulidis, KE Koumarelas, MN Kouliou… - International Journal of …, 2024 - mdpi.com
Gastric cancer (GC) remains a significant contributor to cancer-related mortality. Novel high-
throughput techniques have enlightened the epigenetic mechanisms governing gene …

[HTML][HTML] Epigenetic mechanisms in gastric cancer: potential new therapeutic opportunities

M Canale, A Casadei-Gardini, P Ulivi… - International Journal of …, 2020 - mdpi.com
Gastric cancer (GC) is one of the deadliest malignancies worldwide. Complex disease
heterogeneity, late diagnosis, and suboptimal therapies result in the poor prognosis of …

APC Promoter Methylation in Gastrointestinal Cancer

L Zhu, X Li, Y Yuan, C Dong, M Yang - Frontiers in Oncology, 2021 - frontiersin.org
The adenomatous polyposis coli (APC) gene, known as tumor suppressor gene, has the two
promoters 1A and 1B. Researches on APC have usually focused on its loss-of-function …

Ginsenoside Rg5 as an anticancer drug: a comprehensive review on mechanisms, structure–activity relationship, and prospects for clinical advancement

T Elsaman, AM Muddathir, EAM Mohieldin… - Pharmacological …, 2024 - Springer
Cancer remains one of the leading causes of death in the world. Despite the considerable
success of conventional treatment strategies, the incidence and mortality rates are still high …

A pan-cancer analysis on the carcinogenic effect of human adenomatous polyposis coli

Y Zhang, X Liu, A Li, X Tang - PLoS One, 2022 - journals.plos.org
Adenomatous polyposis coli (APC) is the most commonly mutated gene in colon cancer and
can cause familial adenomatous polyposis (FAP). Hypermethylation of the APC promoter …

APC gene promoter methylation as a potential biomarker for lung cancer diagnosis: A meta‐analysis

F Liu, X Lu, X Zhou, H Huang - Thoracic cancer, 2021 - Wiley Online Library
Background The aim of this study was to quantitatively analysis the diagnostic performance
of adenomatous polyposis coli (APC) gene promoter methylation in serum or sputum …

Diagnostic, prognostic, and predictive biomarkers in gastric cancer: from conventional to novel biomarkers

G Khalili-Tanha, N Khalili-Tanha, AK Rouzbahani… - Translational …, 2024 - Elsevier
Gastric cancer is a major health concern worldwide. The survival rate of Gastric cancer
greatly depends on the stage at which it is diagnosed. Early diagnosis is critical for …

An overview: genetic tumor markers for early detection and current gene therapy strategies

R Quraish, T Hirahata, A Quraish… - Cancer …, 2023 - journals.sagepub.com
Genomic instability is considered a fundamental factor involved in any neoplastic disease.
Consequently, the genetically unstable cells contribute to intratumoral genetic heterogeneity …

LncRNA LINC01278 regulates the prognosis and related mechanisms of gastric cancer by targeting miR-129-5p

Z Wang, L Liu, Z Li, X Liu, J Wang… - Journal of …, 2024 - dl.begellhouse.com
Gastric cancer, a prevalent malady within the digestive tract, has a complex pathological
mechanism and numerous patients. The regulation of gastric cancer process by long non …

Systems biology and OMIC data integration to understand gastrointestinal cancers

IMC Bispo, HP Granger, PP Almeida… - World Journal of …, 2022 - pmc.ncbi.nlm.nih.gov
Gastrointestinal (GI) cancers are a set of diverse diseases affecting many parts/organs. The
five most frequent GI cancer types are esophageal, gastric cancer (GC), liver cancer …