The promise of nanoparticles-based radiotherapy in cancer treatment

M Haque, MS Shakil, KM Mahmud - Cancers, 2023 - mdpi.com
Simple Summary Radiotherapy (RT) is used worldwide as a gold standard treatment
approach for cancer management. However, the RT treatment modality contains limitations …

Current status and future perspectives of gold nanoparticle vectors for siRNA delivery

Á Artiga, I Serrano-Sevilla, L De Matteis… - Journal of Materials …, 2019 - pubs.rsc.org
Discovering the vast therapeutic potential of siRNA opened up new clinical research areas
focussing on a number of diseases and applications; however significant problems with …

Biogenic selenium nanoparticles induce ROS-mediated necroptosis in PC-3 cancer cells through TNF activation

P Sonkusre, SS Cameotra - Journal of nanobiotechnology, 2017 - Springer
Background Selenium is well documented to inhibit cancer at higher doses; however, the
mechanism behind this inhibition varies widely depending on the cell type and selenium …

GLUT1 and GLUT3 involvement in anthocyanin gastric transport-Nanobased targeted approach

H Oliveira, C Roma-Rodrigues, A Santos, B Veigas… - Scientific Reports, 2019 - nature.com
Anthocyanins may protect against a myriad of human diseases. However few studies have
been conducted to evaluate their bioavailability so their absorption mechanism remains …

Atom transfer radical polymerization of multishelled cationic corona for the systemic delivery of siRNA

HS Kim, YJ Son, W Mao, KW Leong, HS Yoo - Nano Letters, 2018 - ACS Publications
We propose an effective siRNA delivery system by preparing poly (DAMA-HEMA)-
multilayered gold nanoparticles using multiple surface-initiated atom transfer radical …

Capacity of gold nanoparticles in cancer radiotherapy

NMS Nagi, YAM Khair, AME Abdalla - Japanese Journal of Radiology, 2017 - Springer
Radiotherapy is the ionizing radiation used for treatment of cancer and other diseases.
Although radiotherapy is the major treatment for cancer, a lot of patients do not undergo …

A review on selenium and gold nanoparticles combined photodynamic and photothermal prostate cancer tumors ablation

OC Omiyale, M Musa, AI Otuyalo, TJ Gbayisomore… - Discover Nano, 2023 - Springer
The acceptance of nanoparticle technology in the quest for cancer treatment is due to its
many potentials and possibilities of filling in the gaps in the limitations of the current …

Powering up the molecular therapy of RNA interference by novel nanoparticles

W Liao, W Li, T Zhang, M Kirberger, J Liu… - Biomaterials …, 2016 - pubs.rsc.org
RNA interference technology has been widely applied in biomedical therapy in recent years.
A type of small RNA molecule–siRNA could regulate the expression of disease related …

Nanoparticle-antagomiR based targeting of miR-31 to induce osterix and osteocalcin expression in mesenchymal stem cells

M McCully, J Conde, P V. Baptista, M Mullin, MJ Dalby… - Plos one, 2018 - journals.plos.org
Mesenchymal stem cells are multipotent adult stem cells capable of generating bone,
cartilage and fat, and are thus currently being exploited for regenerative medicine. When …

Peptide generated anisotropic gold nanoparticles as efficient siRNA vectors

B Panigrahi, S Mishra, RK Singh, N Siddiqui… - International Journal of …, 2019 - Elsevier
Based on the cell penetrating ability of tryptophan-containing peptides, eight linear
hexapeptides have been designed, synthesized and explored their efficiency toward the …