Silicone oil in vitreoretinal surgery: indications, complications, new developments and alternative long‐term tamponade agents

Y Chen, VR Kearns, L Zhou, T Sandinha… - Acta …, 2021 - Wiley Online Library
Silicone oil (SO) has been used as a long‐term tamponade agent in the treatment of
complicated vitreoretinal diseases for about half a century, during which time many …

Retinal and corneal changes associated with intraocular silicone oil tamponade

M Ferrara, G Coco, T Sorrentino, KM Jasani… - Journal of Clinical …, 2022 - mdpi.com
Silicone oils (SO) are used as long-term intraocular tamponades and have an irreplaceable
role in vitreoretinal surgery. They can, however, be associated with multiple and potentially …

Organ-on-a-chip technologies that can transform ophthalmic drug discovery and disease modeling

JC Haderspeck, J Chuchuy, S Kustermann… - Expert opinion on …, 2019 - Taylor & Francis
Introduction: Disorders of the eye that lead to visual impairment are affecting millions of
people worldwide. Nevertheless, for many of these disorders, there are still no effective …

Biocompatibility of intraocular liquid tamponade agents: an update

MR Romano, M Ferrara, I Nepita, J D'Amato Tothova… - Eye, 2021 - nature.com
Intraocular liquids tamponade agents, such as perfluorocarbon liquids (PFCLs),
semifluorinated alkanes (SFAs), silicone oils (SOs) and heavy silicone oils (HSOs), are a …

Heavy and standard silicone oil: intraocular inflammation

A Russo, F Morescalchi, S Donati, E Gambicorti… - International …, 2018 - Springer
Purpose Proliferative vitreoretinopathy in the inferior retina remains clinically challenging.
Heavier-than-water intraocular tamponades have been developed to improve inferior …

Physicochemical properties of explanted silicone oil after use as an intraocular tamponade

M Hammer, S Schickhardt, DJ Munro… - … Vision Science & …, 2022 - tvst.arvojournals.org
Purpose: We studied the effects of exposure to biological media within the eye, such as
contamination with lipophilic and amphiphilic substances, on the physicochemical …

[HTML][HTML] Can wall shear-stress topology predict proliferative vitreoretinopathy localization following pars plana vitrectomy?

PG Ledda, T Rossi, MG Badas, G Querzoli - Journal of Biomechanics, 2024 - Elsevier
We numerically study the fluid dynamics of oil tamponade in models of vitrectomized eyes
prompted by a subset of daily activities corresponding to movements on the horizontal plane …

Emulsification of different viscosity silicone oil in complicated retinal detachment surgery: a randomized double-blinded clinical trial

T Ratanapakorn, W Thongmee… - Clinical …, 2020 - Taylor & Francis
Objective To study silicone oil (SO) emulsification, anatomic and visual outcome after
complicated retinal detachment surgery by pars plana vitrectomy (PPV) with intraocular SO …

In vitro modeling of emulsification of silicone oil as intraocular tamponade using microengineered eye-on-a-chip

YK Chan, KHS Sy, CY Wong, PK Man… - … & Visual Science, 2015 - iovs.arvojournals.org
Purpose.: There is a lack of a standardized methodology or a physiologically realistic in vitro
model to investigate silicone oil (SO) emulsification. In this study, we replicated the SO …

[HTML][HTML] Viscoelastic, optical, and surgical properties of vitreous body replacement hydrogels after aging compared to porcine vitreous bodies and silicone oils

M Hammer, M Muuss, L Herbster… - … Vision Science & …, 2024 - iovs.arvojournals.org
Purpose: First-(monomers), second-(pre-gelated), and third-(in situ gelating after injection)
generation hydrogels were previously introduced to replace the vitreous body after …