Unsupervised machine learning for exploratory data analysis in imaging mass spectrometry

N Verbeeck, RM Caprioli… - Mass spectrometry …, 2020 - Wiley Online Library
Imaging mass spectrometry (IMS) is a rapidly advancing molecular imaging modality that
can map the spatial distribution of molecules with high chemical specificity. IMS does not …

MALDI-MSI towards multimodal imaging: challenges and perspectives

M Tuck, F Grélard, L Blanc, N Desbenoit - Frontiers in Chemistry, 2022 - frontiersin.org
Multimodal imaging is a powerful strategy for combining information from multiple images. It
involves several fields in the acquisition, processing and interpretation of images. As …

Multimodal imaging based on vibrational spectroscopies and mass spectrometry imaging applied to biological tissue: a multiscale and multiomics review

M Tuck, L Blanc, R Touti, NH Patterson… - Analytical …, 2020 - ACS Publications
Molecular imaging has the potential to unearth important spatial and temporal relationships
in biological systems, including intercellular signaling as well as environmentally-cued …

A review on recent machine learning applications for imaging mass spectrometry studies

A Jetybayeva, N Borodinov, AV Ievlev… - Journal of Applied …, 2023 - pubs.aip.org
Imaging mass spectrometry (IMS) is a powerful analytical technique widely used in biology,
chemistry, and materials science fields that continue to expand. IMS provides a qualitative …

Recent advances in mass spectrometry imaging combined with artificial intelligence for spatially clarifying molecular profiles: Toward biomedical applications

H Zhang, J Zhang, C Yuan, D Zhang, D Lu… - TrAC Trends in …, 2024 - Elsevier
Mass spectrometry imaging (MSI) is an intuitive and multidimensional analysis method that
provides spatial information on molecules in tissues or cells; it is widely used in biomedical …

Dimensionality reduction of mass spectrometry imaging data using autoencoders

SA Thomas, AM Race, RT Steven… - … symposium series on …, 2016 - ieeexplore.ieee.org
The use of mass spectrometry imaging (MSI) techniques has become a powerful tool in the
fields of biology, pharmacology and healthcare. Next generation experimental techniques …

Spatio-temporal metabolite profiling of the barley germination process by MALDI MS imaging

K Gorzolka, J Kölling, TW Nattkemper, K Niehaus - PLoS One, 2016 - journals.plos.org
MALDI mass spectrometry imaging was performed to localize metabolites during the first
seven days of the barley germination. Up to 100 mass signals were detected of which 85 …

Spatially aware clustering of ion images in mass spectrometry imaging data using deep learning

W Zhang, M Claesen, T Moerman… - Analytical and …, 2021 - Springer
Computational analysis is crucial to capitalize on the wealth of spatio-molecular information
generated by mass spectrometry imaging (MSI) experiments. Currently, the spatial …

The journey towards clinical adoption of MALDI‐MS‐based imaging proteomics: from current challenges to future expectations

I Piga, F Magni, A Smith - FEBS letters, 2024 - Wiley Online Library
Among the spatial omics techniques available, mass spectrometry imaging (MSI) represents
one of the most promising owing to its capability to map the distribution of hundreds of …

Data filtering and its prioritization in pipelines for spatial segmentation of mass spectrometry imaging

L Guo, Z Hu, C Zhao, X Xu, S Wang, J Xu… - Analytical …, 2021 - ACS Publications
Mass spectrometry imaging (MSI) could provide vast amounts of data at the temporal–spatial
scale in heterogeneous biological specimens, which challenges us to segment accurately …