International Union of Basic and Clinical Pharmacology. CVI: GABAA receptor subtype-and function-selective ligands: key issues in translation to humans
GABA A receptors are the major inhibitory transmitter receptors in the brain. They are ligand-
gated chloride channels and the site of action of benzodiazepines, barbiturates, neuroactive …
gated chloride channels and the site of action of benzodiazepines, barbiturates, neuroactive …
GABA Not Only a Neurotransmitter: Osmotic Regulation by GABAAR Signaling
T Cesetti, F Ciccolini, Y Li - Frontiers in cellular neuroscience, 2012 - frontiersin.org
Mature macroglia and almost all neural progenitor types express γ-aminobutyric (GABA) A
receptors (GABAARs), whose activation by ambient or synaptic GABA, leads to influx or …
receptors (GABAARs), whose activation by ambient or synaptic GABA, leads to influx or …
Dysregulation of the long non-coding RNA transcriptome in a Rett syndrome mouse model
Mecp2 is a transcriptional repressor protein that is mutated in Rett syndrome, a
neurodevelopmental disorder that is the second most common cause of mental retardation …
neurodevelopmental disorder that is the second most common cause of mental retardation …
GABAA Receptors Containing ρ1 Subunits Contribute to In Vivo Effects of Ethanol in Mice
YA Blednov, JM Benavidez, M Black, CR Leiter… - PloS one, 2014 - journals.plos.org
GABAA receptors consisting of ρ1, ρ2, or ρ3 subunits in homo-or hetero-pentamers have
been studied mainly in retina but are detected in many brain regions. Receptors formed from …
been studied mainly in retina but are detected in many brain regions. Receptors formed from …
Modulation of dopamine release by ethanol is mediated by atypical GABAA receptors on cholinergic interneurons in the nucleus accumbens
JT Yorgason, HA Wadsworth, EJ Anderson… - Addiction …, 2022 - Wiley Online Library
Previous studies indicate that moderate‐to‐high ethanol (EtOH) concentrations enhance
dopamine (DA) neurotransmission in the mesolimbic DA system from the ventral tegmental …
dopamine (DA) neurotransmission in the mesolimbic DA system from the ventral tegmental …
Complex inhibitory microcircuitry regulates retinal signaling near visual threshold
Neuronal microcircuits, small, localized signaling motifs involving two or more neurons,
underlie signal processing and computation in the brain. Compartmentalized signaling …
underlie signal processing and computation in the brain. Compartmentalized signaling …
Differential localization of γ‐aminobutyric acid type a and glycine receptor subunits and gephyrin in the human pons, medulla oblongata and uppermost cervical …
HJ Waldvogel, K Baer, E Eady, KL Allen… - Journal of …, 2010 - Wiley Online Library
Gephyrin is a multifunctional protein responsible for the clustering of glycine receptors
(GlyR) and γ‐aminobutyric acid type A receptors (GABAAR). GlyR and GABAAR are …
(GlyR) and γ‐aminobutyric acid type A receptors (GABAAR). GlyR and GABAAR are …
Estrogen in cycling rats alters gene expression in the temporomandibular joint, trigeminal ganglia and trigeminal subnucleus caudalis/upper cervical cord junction
Females report temporomandibular joint (TMJ) pain more than men and studies suggest
estrogen modulates this pain response. Our goal in this study was to determine genes that …
estrogen modulates this pain response. Our goal in this study was to determine genes that …
Presynaptic inhibition of primary afferents by depolarization: observations supporting nontraditional mechanisms
S Hochman, J Shreckengost, H Kimura… - Annals of the New …, 2010 - Wiley Online Library
Primary afferent neurotransmission is the fundamental first step in the central processing of
sensory stimuli and is controlled by pre‐and postsynaptic inhibitory mechanisms …
sensory stimuli and is controlled by pre‐and postsynaptic inhibitory mechanisms …
[HTML][HTML] Reductions in calcium signaling limit inhibition to diabetic retinal rod bipolar cells
JM Moore-Dotson, ED Eggers - Investigative Ophthalmology & …, 2019 - jov.arvojournals.org
Purpose: The balance of neuronal excitation and inhibition is important for proper retinal
signaling. A previous report showed that diabetes selectively reduces light-evoked inhibition …
signaling. A previous report showed that diabetes selectively reduces light-evoked inhibition …