International Union of Basic and Clinical Pharmacology. CVI: GABAA receptor subtype-and function-selective ligands: key issues in translation to humans

W Sieghart, MM Savić, EH Ohlstein - Pharmacological reviews, 2018 - Elsevier
GABA A receptors are the major inhibitory transmitter receptors in the brain. They are ligand-
gated chloride channels and the site of action of benzodiazepines, barbiturates, neuroactive …

GABA Not Only a Neurotransmitter: Osmotic Regulation by GABAAR Signaling

T Cesetti, F Ciccolini, Y Li - Frontiers in cellular neuroscience, 2012 - frontiersin.org
Mature macroglia and almost all neural progenitor types express γ-aminobutyric (GABA) A
receptors (GABAARs), whose activation by ambient or synaptic GABA, leads to influx or …

Dysregulation of the long non-coding RNA transcriptome in a Rett syndrome mouse model

P Petazzi, J Sandoval, K Szczesna, OC Jorge, L Roa… - RNA biology, 2013 - Taylor & Francis
Mecp2 is a transcriptional repressor protein that is mutated in Rett syndrome, a
neurodevelopmental disorder that is the second most common cause of mental retardation …

GABAA Receptors Containing ρ1 Subunits Contribute to In Vivo Effects of Ethanol in Mice

YA Blednov, JM Benavidez, M Black, CR Leiter… - PloS one, 2014 - journals.plos.org
GABAA receptors consisting of ρ1, ρ2, or ρ3 subunits in homo-or hetero-pentamers have
been studied mainly in retina but are detected in many brain regions. Receptors formed from …

Modulation of dopamine release by ethanol is mediated by atypical GABAA receptors on cholinergic interneurons in the nucleus accumbens

JT Yorgason, HA Wadsworth, EJ Anderson… - Addiction …, 2022 - Wiley Online Library
Previous studies indicate that moderate‐to‐high ethanol (EtOH) concentrations enhance
dopamine (DA) neurotransmission in the mesolimbic DA system from the ventral tegmental …

Complex inhibitory microcircuitry regulates retinal signaling near visual threshold

WN Grimes, J Zhang, H Tian… - Journal of …, 2015 - journals.physiology.org
Neuronal microcircuits, small, localized signaling motifs involving two or more neurons,
underlie signal processing and computation in the brain. Compartmentalized signaling …

Differential localization of γ‐aminobutyric acid type a and glycine receptor subunits and gephyrin in the human pons, medulla oblongata and uppermost cervical …

HJ Waldvogel, K Baer, E Eady, KL Allen… - Journal of …, 2010 - Wiley Online Library
Gephyrin is a multifunctional protein responsible for the clustering of glycine receptors
(GlyR) and γ‐aminobutyric acid type A receptors (GABAAR). GlyR and GABAAR are …

Estrogen in cycling rats alters gene expression in the temporomandibular joint, trigeminal ganglia and trigeminal subnucleus caudalis/upper cervical cord junction

J Puri, LL Bellinger, PR Kramer - Journal of cellular physiology, 2011 - Wiley Online Library
Females report temporomandibular joint (TMJ) pain more than men and studies suggest
estrogen modulates this pain response. Our goal in this study was to determine genes that …

Presynaptic inhibition of primary afferents by depolarization: observations supporting nontraditional mechanisms

S Hochman, J Shreckengost, H Kimura… - Annals of the New …, 2010 - Wiley Online Library
Primary afferent neurotransmission is the fundamental first step in the central processing of
sensory stimuli and is controlled by pre‐and postsynaptic inhibitory mechanisms …

[HTML][HTML] Reductions in calcium signaling limit inhibition to diabetic retinal rod bipolar cells

JM Moore-Dotson, ED Eggers - Investigative Ophthalmology & …, 2019 - jov.arvojournals.org
Purpose: The balance of neuronal excitation and inhibition is important for proper retinal
signaling. A previous report showed that diabetes selectively reduces light-evoked inhibition …