DNA and RNA can adopt various secondary structures. Four-stranded G-quadruplex (G4)
structures form through self-recognition of guanines into stacked tetrads, and considerable …

In recent years, nanopore technology has become increasingly important in the field of life
science and biomedical research. By embedding a nano-scale hole in a thin membrane and …

Guanine-rich sequences can form G-quadruplexes (G4) in living cells, making these
structures promising anti-cancer targets. Compounds able to recognize these structures …

Abstract G-quadruplexes (G4s) are non-canonical nucleic acids secondary structures that
form within guanine-rich strands of regulatory genomic regions. G4s have been extensively …

DNA and RNA can fold into a variety of alternative conformations. In recent years, a
particular nucleic acid structure was discussed to play a role in malignant transformation and …

In addition to the canonical double helix, DNA can fold into various other inter-and
intramolecular secondary structures. Although many such structures were long thought to be …

A G-quadruplex (G4) is a well-known nucleic acid secondary structure comprising guanine-
rich sequences, and has profound implications for various pharmacological and biological …

Progress in the design of G-quadruplex (G4) binding ligands relies on the availability of
approaches that assess the binding mode and nature of the interactions between G4 …

G-quadruplexes are four-stranded DNA structures that are over-represented in gene
promoter regions and are viewed as emerging therapeutic targets in oncology, as …

Conspectus G-quadruplexes (G4s) are distinctive four-stranded DNA or RNA structures
found within cells that are thought to play functional roles in gene regulation and …