Myelin plasticity: sculpting circuits in learning and memory
Throughout our lifespan, new sensory experiences and learning continually shape our
neuronal circuits to form new memories. Plasticity at the level of synapses has been …
neuronal circuits to form new memories. Plasticity at the level of synapses has been …
[HTML][HTML] Myelin in the central nervous system: structure, function, and pathology
C Stadelmann, S Timmler… - Physiological …, 2019 - journals.physiology.org
Oligodendrocytes generate multiple layers of myelin membrane around axons of the central
nervous system to enable fast and efficient nerve conduction. Until recently, saltatory nerve …
nervous system to enable fast and efficient nerve conduction. Until recently, saltatory nerve …
Microglia phagocytose myelin sheaths to modify developmental myelination
AN Hughes, B Appel - Nature neuroscience, 2020 - nature.com
During development, oligodendrocytes contact and wrap neuronal axons with myelin.
Similarly to neurons and synapses, excess myelin sheaths are produced and selectively …
Similarly to neurons and synapses, excess myelin sheaths are produced and selectively …
[HTML][HTML] The cingulum bundle: Anatomy, function, and dysfunction
The cingulum bundle is a prominent white matter tract that interconnects frontal, parietal, and
medial temporal sites, while also linking subcortical nuclei to the cingulate gyrus. Despite its …
medial temporal sites, while also linking subcortical nuclei to the cingulate gyrus. Despite its …
Periods of synchronized myelin changes shape brain function and plasticity
Myelin, a lipid membrane that wraps axons, enabling fast neurotransmission and metabolic
support to axons, is conventionally thought of as a static structure that is set early in …
support to axons, is conventionally thought of as a static structure that is set early in …
Myelin: A gatekeeper of activity-dependent circuit plasticity?
BACKGROUND Myelin, produced by oligodendrocytes, supports the rapid and
synchronized transfer of information across the central nervous system (CNS). Earlier views …
synchronized transfer of information across the central nervous system (CNS). Earlier views …
Motor learning promotes remyelination via new and surviving oligodendrocytes
Oligodendrocyte loss in neurological disease leaves axons vulnerable to damage and
degeneration, and activity-dependent myelination may represent an endogenous …
degeneration, and activity-dependent myelination may represent an endogenous …
Oligodendrocyte progenitor cells become regionally diverse and heterogeneous with age
SO Spitzer, S Sitnikov, Y Kamen, KA Evans… - Neuron, 2019 - cell.com
Oligodendrocyte progenitor cells (OPCs), which differentiate into myelinating
oligodendrocytes during CNS development, are the main proliferative cells in the adult …
oligodendrocytes during CNS development, are the main proliferative cells in the adult …
Differentiation and maturation of oligodendrocytes in human three-dimensional neural cultures
Investigating human oligodendrogenesis and the interaction of oligodendrocytes with
neurons and astrocytes would accelerate our understanding of the mechanisms underlying …
neurons and astrocytes would accelerate our understanding of the mechanisms underlying …
A new mechanism of nervous system plasticity: activity-dependent myelination
RD Fields - Nature Reviews Neuroscience, 2015 - nature.com
The synapse is the focus of experimental research and theory on the cellular mechanisms of
nervous system plasticity and learning, but recent research is expanding the consideration …
nervous system plasticity and learning, but recent research is expanding the consideration …