Myelin plasticity: sculpting circuits in learning and memory

W **n, JR Chan - Nature Reviews Neuroscience, 2020 - nature.com
Throughout our lifespan, new sensory experiences and learning continually shape our
neuronal circuits to form new memories. Plasticity at the level of synapses has been …

[HTML][HTML] Myelin in the central nervous system: structure, function, and pathology

C Stadelmann, S Timmler… - Physiological …, 2019 - journals.physiology.org
Oligodendrocytes generate multiple layers of myelin membrane around axons of the central
nervous system to enable fast and efficient nerve conduction. Until recently, saltatory nerve …

Microglia phagocytose myelin sheaths to modify developmental myelination

AN Hughes, B Appel - Nature neuroscience, 2020 - nature.com
During development, oligodendrocytes contact and wrap neuronal axons with myelin.
Similarly to neurons and synapses, excess myelin sheaths are produced and selectively …

[HTML][HTML] The cingulum bundle: Anatomy, function, and dysfunction

EJ Bubb, C Metzler-Baddeley, JP Aggleton - … & Biobehavioral Reviews, 2018 - Elsevier
The cingulum bundle is a prominent white matter tract that interconnects frontal, parietal, and
medial temporal sites, while also linking subcortical nuclei to the cingulate gyrus. Despite its …

Periods of synchronized myelin changes shape brain function and plasticity

O de Faria Jr, H Pivonkova, B Varga, S Timmler… - Nature …, 2021 - nature.com
Myelin, a lipid membrane that wraps axons, enabling fast neurotransmission and metabolic
support to axons, is conventionally thought of as a static structure that is set early in …

Myelin: A gatekeeper of activity-dependent circuit plasticity?

G Bonetto, D Belin, RT Káradóttir - Science, 2021 - science.org
BACKGROUND Myelin, produced by oligodendrocytes, supports the rapid and
synchronized transfer of information across the central nervous system (CNS). Earlier views …

Motor learning promotes remyelination via new and surviving oligodendrocytes

CM Bacmeister, HJ Barr, CR McClain… - Nature …, 2020 - nature.com
Oligodendrocyte loss in neurological disease leaves axons vulnerable to damage and
degeneration, and activity-dependent myelination may represent an endogenous …

Oligodendrocyte progenitor cells become regionally diverse and heterogeneous with age

SO Spitzer, S Sitnikov, Y Kamen, KA Evans… - Neuron, 2019 - cell.com
Oligodendrocyte progenitor cells (OPCs), which differentiate into myelinating
oligodendrocytes during CNS development, are the main proliferative cells in the adult …

Differentiation and maturation of oligodendrocytes in human three-dimensional neural cultures

RM Marton, Y Miura, SA Sloan, Q Li, O Revah… - Nature …, 2019 - nature.com
Investigating human oligodendrogenesis and the interaction of oligodendrocytes with
neurons and astrocytes would accelerate our understanding of the mechanisms underlying …

A new mechanism of nervous system plasticity: activity-dependent myelination

RD Fields - Nature Reviews Neuroscience, 2015 - nature.com
The synapse is the focus of experimental research and theory on the cellular mechanisms of
nervous system plasticity and learning, but recent research is expanding the consideration …