Cardiovascular diseases (CVDs) are pointed out by the World Health Organization (WHO)
as the leading cause of death, contributing to a significant and growing global health and …

During the last two decades, significant progress has been made in the identification of
genetic defects underlying inherited arrhythmia syndromes, which has provided some …

Human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) are increasingly
used for personalised medicine and preclinical cardiotoxicity testing. Reports on hiPSC-CM …

Bisphenol A (BPA) is a well-known endocrine-disrupting chemical that is widely used in a
variety of products, including plastics, medical equipment and receipts. Hence, most people …

Ten years ago Yamanaka's lab identified a way to reprogram terminally differentiated cells to
a pluripotent state, similar to that of embryonic stem cell. This procedure opened the road for …

Vandetanib, a multi-kinase inhibitor used for the treatment of various cancers, has been
reported to induce several adverse cardiac effects. However, the underlying mechanisms of …

Despite major efforts by clinicians and researchers, cardiac arrhythmia remains a leading
cause of morbidity and mortality in the world. Experimental work has relied on combining …

Aripiprazole is an atypical antipsychotic drug, which is prescribed for many psychiatric
diseases such as schizophrenia and mania in bipolar disorder. It primarily acts as an agonist …

Induced pluripotent stem cells (iPSCs) are powerful tools for investigating the relationship
between genotype and phenotype. Recent publications have described iPSC cohort studies …

Cardiovascular diseases (CVDs) are widespread in the modern world, and their number is
constantly growing. For a long time, CVDs have been the leading cause of morbidity and …