Electrochemical methods for the analysis of clinically relevant biomolecules

M Labib, EH Sargent, SO Kelley - Chemical reviews, 2016 - ACS Publications
Rapid progress in identifying biomarkers that are hallmarks of disease has increased
demand for high-performance detection technologies. Implementation of electrochemical …

Nucleic acid tests for clinical translation

M Li, F Yin, L Song, X Mao, F Li, C Fan, X Zuo… - Chemical …, 2021 - ACS Publications
Nucleic acids, including deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), are
natural biopolymers composed of nucleotides that store, transmit, and express genetic …

Recent advances and challenges in electrochemical biosensors for emerging and re-emerging infectious diseases

S Menon, MR Mathew, S Sam, K Keerthi… - Journal of …, 2020 - Elsevier
The rise of emerging infectious diseases (EIDs) as well as the increase in spread of existing
infections is threatening global economies and human lives, with several countries still …

Biomarker detection technologies and future directions

SB Nimse, MD Sonawane, KS Song, T Kim - Analyst, 2016 - pubs.rsc.org
Biomarkers play a vital role in disease detection and treatment follow-up. It is important to
note that diseases in the early stage are typically treated with the greatest probability of …

Boronate affinity-based electrochemical aptasensor for point-of-care glycoprotein detection

Q Hu, S Hu, S Li, S Liu, Y Liang, X Cao, Y Luo… - Analytical …, 2022 - ACS Publications
As a class of oligosaccharide chain-containing proteins, glycoproteins are of great value in
screening and early diagnosis of malignant tumors and other major diseases. Herein, we …

Electrochemical biosensors with aptamer recognition layer for the diagnosis of pathogenic bacteria: Barriers to commercialization and remediation

M Al Mamun, YA Wahab, MAM Hossain… - TrAC Trends in …, 2021 - Elsevier
One of the serious public health threats is pathogenic bacteria due to the lack of affordable
and early-stage diagnosis and treatment. The existing diagnostic methods are tedious, time …

Current advances in aptamers for cancer diagnosis and therapy

S Hori, A Herrera, JJ Rossi, J Zhou - Cancers, 2018 - mdpi.com
Nucleic acid aptamers are single-stranded oligonucleotides that interact with target
molecules with high affinity and specificity in unique three-dimensional structures. Aptamers …

Application of various optical and electrochemical aptasensors for detection of human prostate specific antigen: A review

F Ghorbani, H Abbaszadeh, JEN Dolatabadi… - Biosensors and …, 2019 - Elsevier
Early stage detection of prostate cancer, one of the main causes of mortality among men, is
of great importance for better treatment of the patients. Prostate specific antigen (PSA) is a …

Electrochemically controlled ATRP for cleavage-based electrochemical detection of the prostate-specific antigen at femtomolar level concentrations

Q Hu, S Gan, Y Bao, Y Zhang, D Han, L Niu - Analytical Chemistry, 2020 - ACS Publications
As a single-chain glycoprotein with endopeptidase activity, the prostate-specific antigen
(PSA) is valuable as an informative serum marker in diagnosing, staging, and prognosis of …

Electrochemical aptamer-based bioplatform for ultrasensitive detection of prostate specific antigen

A Raouafi, A Sánchez, N Raouafi… - Sensors and Actuators B …, 2019 - Elsevier
A novel and disposable potentio-amperometric aptasensor for the prostate specific antigen
(PSA) was constructed using functionalized graphene-modified carbon screen-printed …