Precision diagnostics is one of the two pillars of precision medicine. Sequencing efforts in
the past decade have firmly established cancer as a primarily genetically driven disease …

Simple Summary Breast cancer is a heterogeneous disease that is driven by genetic,
epigenetic and phenotypic modifications and is also affected by the microenvironment and …

Background Addition of CDK4/6 inhibitors (CDK4/6i) to endocrine therapy significantly
increased progression-free survival, leading to their approval and incorporation into the …

As genetic testing becomes increasingly more accessible and more applicable with a
broader range of clinical implications, it may also become more challenging for breast …

Breast cancer is a global health issue. For decades, breast cancer was classified into many
histological subtypes on the basis of microscopic and immunohistochemical evaluation. The …

Multicellular tumor spheroid (MCTS) systems provide an in vitro cell culture model system
which mimics many of the complexities of an in vivo solid tumor and tumor …

Breast cancer (BC) is the most common cancer among women worldwide, with a
progressive increase in its incidence. It is the second leading cause of cancer-related death …

Breast cancer therapeutic regimens are currently administered in a structured and pre-
determined manner with drug and dosing strategies determined based on broad molecular …