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[HTML][HTML] Advanced machine-learning techniques in drug discovery
Highlights•Machine learning techniques (MLTs) are progressing the drug discovery
process.•Conventional MLTs require large data, lack transparency and are not …
process.•Conventional MLTs require large data, lack transparency and are not …
Application of deep learning on single-cell RNA sequencing data analysis: a review
Single-cell RNA sequencing (scRNA-seq) has become a routinely used technique to
quantify the gene expression profile of thousands of single cells simultaneously. Analysis of …
quantify the gene expression profile of thousands of single cells simultaneously. Analysis of …
[HTML][HTML] Computational approaches to explainable artificial intelligence: advances in theory, applications and trends
Deep Learning (DL), a groundbreaking branch of Machine Learning (ML), has emerged as a
driving force in both theoretical and applied Artificial Intelligence (AI). DL algorithms, rooted …
driving force in both theoretical and applied Artificial Intelligence (AI). DL algorithms, rooted …
[HTML][HTML] Recent advances and application of generative adversarial networks in drug discovery, development, and targeting
A rising amount of research demonstrates that artificial intelligence and machine learning
approaches can provide an essential basis for the drug design and discovery process. Deep …
approaches can provide an essential basis for the drug design and discovery process. Deep …
[HTML][HTML] Recent advances in generative adversarial networks for gene expression data: a comprehensive review
M Lee - Mathematics, 2023 - mdpi.com
The evolving field of generative artificial intelligence (GenAI), particularly generative deep
learning, is revolutionizing a host of scientific and technological sectors. One of the pivotal …
learning, is revolutionizing a host of scientific and technological sectors. One of the pivotal …
Element selection for crystalline inorganic solid discovery guided by unsupervised machine learning of experimentally explored chemistry
The selection of the elements to combine delimits the possible outcomes of synthetic
chemistry because it determines the range of compositions and structures, and thus …
chemistry because it determines the range of compositions and structures, and thus …
[HTML][HTML] Deep learning with neuroimaging and genomics in Alzheimer's disease
A growing body of evidence currently proposes that deep learning approaches can serve as
an essential cornerstone for the diagnosis and prediction of Alzheimer's disease (AD). In …
an essential cornerstone for the diagnosis and prediction of Alzheimer's disease (AD). In …
[HTML][HTML] Relevant applications of generative adversarial networks in drug design and discovery: molecular de novo design, dimensionality reduction, and de novo …
A growing body of evidence now suggests that artificial intelligence and machine learning
techniques can serve as an indispensable foundation for the process of drug design and …
techniques can serve as an indispensable foundation for the process of drug design and …
A comprehensive survey of dimensionality reduction and clustering methods for single-cell and spatial transcriptomics data
Y Sun, L Kong, J Huang, H Deng, X Bian… - Briefings in …, 2024 - academic.oup.com
In recent years, the application of single-cell transcriptomics and spatial transcriptomics
analysis techniques has become increasingly widespread. Whether dealing with single-cell …
analysis techniques has become increasingly widespread. Whether dealing with single-cell …
Preprocessing of single cell RNA sequencing data using correlated clustering and projection
Single-cell RNA sequencing (scRNA-seq) is widely used to reveal heterogeneity in cells,
which has given us insights into cell–cell communication, cell differentiation, and differential …
which has given us insights into cell–cell communication, cell differentiation, and differential …