[HTML][HTML] Advanced machine-learning techniques in drug discovery

M Elbadawi, S Gaisford, AW Basit - Drug Discovery Today, 2021 - Elsevier
Highlights•Machine learning techniques (MLTs) are progressing the drug discovery
process.•Conventional MLTs require large data, lack transparency and are not …

Application of deep learning on single-cell RNA sequencing data analysis: a review

M Brendel, C Su, Z Bai, H Zhang… - Genomics …, 2022 - academic.oup.com
Single-cell RNA sequencing (scRNA-seq) has become a routinely used technique to
quantify the gene expression profile of thousands of single cells simultaneously. Analysis of …

[HTML][HTML] Computational approaches to explainable artificial intelligence: advances in theory, applications and trends

JM Górriz, I Álvarez-Illán, A Álvarez-Marquina, JE Arco… - Information …, 2023 - Elsevier
Deep Learning (DL), a groundbreaking branch of Machine Learning (ML), has emerged as a
driving force in both theoretical and applied Artificial Intelligence (AI). DL algorithms, rooted …

[HTML][HTML] Recent advances and application of generative adversarial networks in drug discovery, development, and targeting

S Tripathi, AI Augustin, A Dunlop, R Sukumaran… - Artificial Intelligence in …, 2022 - Elsevier
A rising amount of research demonstrates that artificial intelligence and machine learning
approaches can provide an essential basis for the drug design and discovery process. Deep …

[HTML][HTML] Recent advances in generative adversarial networks for gene expression data: a comprehensive review

M Lee - Mathematics, 2023 - mdpi.com
The evolving field of generative artificial intelligence (GenAI), particularly generative deep
learning, is revolutionizing a host of scientific and technological sectors. One of the pivotal …

Element selection for crystalline inorganic solid discovery guided by unsupervised machine learning of experimentally explored chemistry

A Vasylenko, J Gamon, BB Duff, VV Gusev… - Nature …, 2021 - nature.com
The selection of the elements to combine delimits the possible outcomes of synthetic
chemistry because it determines the range of compositions and structures, and thus …

[HTML][HTML] Deep learning with neuroimaging and genomics in Alzheimer's disease

E Lin, CH Lin, HY Lane - International journal of molecular sciences, 2021 - mdpi.com
A growing body of evidence currently proposes that deep learning approaches can serve as
an essential cornerstone for the diagnosis and prediction of Alzheimer's disease (AD). In …

[HTML][HTML] Relevant applications of generative adversarial networks in drug design and discovery: molecular de novo design, dimensionality reduction, and de novo …

E Lin, CH Lin, HY Lane - Molecules, 2020 - mdpi.com
A growing body of evidence now suggests that artificial intelligence and machine learning
techniques can serve as an indispensable foundation for the process of drug design and …

A comprehensive survey of dimensionality reduction and clustering methods for single-cell and spatial transcriptomics data

Y Sun, L Kong, J Huang, H Deng, X Bian… - Briefings in …, 2024 - academic.oup.com
In recent years, the application of single-cell transcriptomics and spatial transcriptomics
analysis techniques has become increasingly widespread. Whether dealing with single-cell …

Preprocessing of single cell RNA sequencing data using correlated clustering and projection

Y Hozumi, KA Tanemura, GW Wei - Journal of chemical …, 2023 - ACS Publications
Single-cell RNA sequencing (scRNA-seq) is widely used to reveal heterogeneity in cells,
which has given us insights into cell–cell communication, cell differentiation, and differential …