Allenes are the simplest class of cumulenes, possessing unique physical and chemical
properties. These structural units are widely used as valuable synthetic intermediates in …

Propargylic alcohols are readily available bifunctional (alkyne and hydroxyl groups)
synthons, which recognize as one of the attractive synthetic feedstock in organic …

Catalytic functionalization of alkynes with organoboron reagents provides a straightforward
access to stereochemically defined multisubstituted alkenes, which are structural motifs …

An asymmetric organocatalytic remote 1, 10-addition of alkynyl indole imine methides
generated in situ from α-(6-indolyl) propargylic alcohols with thiazolones has been …

Propargylic alcohols have been known as useful substrates in a wide range of asymmetric
reactions. In particular, chiral phosphoric acid (CPA) catalyzed reactions of functionalized …

With the aid of chiral phosphoric acid, enantioselective 1, 6-addition of tryptamines to in situ
formed alkynyl 7-methylene-7H-indoles from tertiary α-(7-indolyl) methanols has been …

We herein demonstrate the acylsilane-directed Rh-catalyzed arene C–H bond alkylation
with maleimides. The resulting derivatives were utilized in visible-light-induced …

A hexafluoroisopropanol (HFIP)-catalyzed difluoroalkylation of propargylic alcohols with
difluoroenoxysilanes to access structurally diverse tetrasubstituted difluoroalkyl allenes has …

The C− H functionalization strategy provides access to valuable molecules that previously
required convoluted synthetic attempts. Dual C− H unsymmetrical functionalization, with a …

We present here a rhodium-catalyzed oxidative three-point double annulation of
enaminones with propargylic alcohols via a C–H and a C–N bond activation to access …