[HTML][HTML] Schwann cell functions in peripheral nerve development and repair
The glial cell of the peripheral nervous system (PNS), the Schwann cell (SC), counts among
the most multifaceted cells of the body. During development, SCs secure neuronal survival …
the most multifaceted cells of the body. During development, SCs secure neuronal survival …
Overview of myelin, major myelin lipids, and myelin-associated proteins
A Kister, I Kister - Frontiers in Chemistry, 2023 - frontiersin.org
Myelin is a modified cell membrane that forms a multilayer sheath around the axon. It retains
the main characteristics of biological membranes, such as lipid bilayer, but differs from them …
the main characteristics of biological membranes, such as lipid bilayer, but differs from them …
Transcriptional profiling of mouse peripheral nerves to the single-cell level to build a sciatic nerve ATlas (SNAT)
Peripheral nerves are organ-like structures containing diverse cell types to optimize function.
This interactive assembly includes mostly axon-associated Schwann cells, but also …
This interactive assembly includes mostly axon-associated Schwann cells, but also …
The epigenetic role of vitamin C in health and disease
V Camarena, G Wang - Cellular and Molecular Life Sciences, 2016 - Springer
Recent advances have uncovered a previously unknown function of vitamin C in epigenetic
regulation. Vitamin C exists predominantly as an ascorbate anion under physiological pH …
regulation. Vitamin C exists predominantly as an ascorbate anion under physiological pH …
Schwann cell precursors; multipotent glial cells in embryonic nerves
KR Jessen, R Mirsky - Frontiers in molecular neuroscience, 2019 - frontiersin.org
The cells of the neural crest, often referred to as neural crest stem cells, give rise to a
number of sub-lineages, one of which is Schwann cells, the glial cells of peripheral nerves …
number of sub-lineages, one of which is Schwann cells, the glial cells of peripheral nerves …
New insights on Schwann cell development
KR Monk, ML Feltri, C Taveggia - Glia, 2015 - Wiley Online Library
In the peripheral nervous system, Schwann cells are glial cells that are in intimate contact
with axons throughout development. Schwann cells generate the insulating myelin sheath …
with axons throughout development. Schwann cells generate the insulating myelin sheath …
Impaired prenatal motor axon development necessitates early therapeutic intervention in severe SMA
L Kong, DO Valdivia, CM Simon… - Science translational …, 2021 - science.org
Gene replacement and pre-mRNA splicing modifier therapies represent breakthrough gene
targeting treatments for the neuromuscular disease spinal muscular atrophy (SMA), but …
targeting treatments for the neuromuscular disease spinal muscular atrophy (SMA), but …
[HTML][HTML] Biomechanical microenvironment in peripheral nerve regeneration: from pathophysiological understanding to tissue engineering development
Peripheral nerve injury (PNI) caused by trauma, chronic disease and other factors may lead
to partial or complete loss of sensory, motor and autonomic functions, as well as neuropathic …
to partial or complete loss of sensory, motor and autonomic functions, as well as neuropathic …
Development of myelinating glia: an overview
Myelin is essential to nervous system function, playing roles in saltatory conduction and
trophic support. Oligodendrocytes (OLs) and Schwann cells (SCs) form myelin in the central …
trophic support. Oligodendrocytes (OLs) and Schwann cells (SCs) form myelin in the central …
YAP and TAZ control peripheral myelination and the expression of laminin receptors in Schwann cells
Myelination is essential for nervous system function. Schwann cells interact with neurons
and the basal lamina to myelinate axons using known receptors, signals and transcription …
and the basal lamina to myelinate axons using known receptors, signals and transcription …