T cells in health and disease

L Sun, Y Su, A Jiao, X Wang, B Zhang - Signal transduction and …, 2023 - nature.com
T cells are crucial for immune functions to maintain health and prevent disease. T cell
development occurs in a stepwise process in the thymus and mainly generates CD4+ and …

Immune responses in mildly versus critically ill COVID-19 patients

H Nasrollahi, AG Talepoor, Z Saleh… - Frontiers in …, 2023 - frontiersin.org
The current coronavirus pandemic (COVID-19), caused by SARS-CoV-2, has had
devastating effects on the global health and economic system. The cellular and molecular …

Autoimmune and autoinflammatory connective tissue disorders following COVID-19

SH Lim, HJ Ju, JH Han, JH Lee, WS Lee… - JAMA network …, 2023 - jamanetwork.com
Importance Multiple cases of autoimmune and autoinflammatory diseases after COVID-19
have been reported. However, their incidences and risks have rarely been quantified …

A high-risk gut microbiota configuration associates with fatal hyperinflammatory immune and metabolic responses to SARS-CoV-2

WC Albrich, TS Ghosh, S Ahearn-Ford, F Mikaeloff… - Gut …, 2022 - Taylor & Francis
Protection against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection
and associated clinical sequelae requires well-coordinated metabolic and immune …

Fc-mediated pan-sarbecovirus protection after alphavirus vector vaccination

LE Adams, SR Leist, KH Dinnon, A West, KL Gully… - Cell Reports, 2023 - cell.com
Group 2B β-coronaviruses (sarbecoviruses) have caused regional and global epidemics in
modern history. Here, we evaluate the mechanisms of cross-sarbecovirus protective …

An intranasal vaccine comprising SARS-CoV-2 spike receptor-binding domain protein entrapped in mannose-conjugated chitosan nanoparticle provides protection in …

K Tabynov, M Solomadin, N Turebekov, M Babayeva… - Scientific Reports, 2023 - nature.com
We developed a novel intranasal SARS-CoV-2 subunit vaccine called NARUVAX-C19/Nano
based on the spike protein receptor-binding domain (RBD) entrapped in mannose …

COVID‐19‐induced autoimmune thyroiditis: Exploring molecular mechanisms

B Mohammadi, K Dua, M Saghafi… - Journal of medical …, 2023 - Wiley Online Library
Severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2) damages multiple
organs, including the thyroid, by direct invasion and cell entry via angiotensin‐converting …

Effect of DMARDs on the immunogenicity of vaccines

Y van Sleen, KSM van der Geest… - Nature Reviews …, 2023 - nature.com
Vaccines are important for protecting individuals at increased risk of severe infections,
including patients undergoing DMARD therapy. However, DMARD therapy can also …

COVID-19 and atrial fibrillation: Intercepting lines

M Donniacuo, A De Angelis, C Rafaniello… - Frontiers in …, 2023 - frontiersin.org
Almost 20% of COVID-19 patients have a history of atrial fibrillation (AF), but also a new-
onset AF represents a frequent complication in COVID-19. Clinical evidence demonstrates …

A recombinant VSV-based bivalent vaccine effectively protects against both SARS-CoV-2 and influenza a virus infection

Z Ao, MJ Ouyang, TA Olukitibi, B Warner… - Journal of …, 2022 - Am Soc Microbiol
ABSTRACT COVID-19 and influenza are both highly contagious respiratory diseases that
have been serious threats to global public health. It is necessary to develop a bivalent …