During Parkinson's disease (PD), both the central nervous system (CNS) and peripheral
nervous system (PNS) are affected. In parallel, innate immune cells respond early to …

Abstract Neurodegenerative diseases (NDs), including Alzheimer's disease (AD),
Parkinson's disease (PD), and amyotrophic lateral sclerosis (ALS), exhibit high phenotypic …

Parkinson disease (PD) is the second most common age-related neurodegenerative
condition diagnosed in North America. We recently demonstrated, using multiple …

Most complex human traits differ by sex, but we have limited insight into the underlying
mechanisms. Here, we investigated the influence of biological sex on protein expression …

Personalized medicine promises individualized disease prediction and treatment. The
convergence of machine learning (ML) and available multimodal data is key moving …

Parkinson's disease (PD) is a complex neurodegenerative condition in which genetic and
environmental factors interact to contribute to its etiology. Remarkable progress has been …

Aims Age and sex are important individual factors modifying the clinical symptoms of
patients with Parkinson's disease (PD). Our goal is to evaluate the effects of age and sex on …

Parkinson's disease (PD) is a neurodegenerative disorder that affects millions of people
worldwide, and its incidence is expected to rise due to the aging of the global population …

ABSTRACT Background Studies of Parkinson's disease (PD) and the association with age
at menarche or menopause have reported inconsistent findings. Mendelian randomization …

Parkinson's disease is a progressive neurological disorder, characterized by prominent
movement dysfunction. The past two decades have seen a rapid expansion of our …